David J Lefer相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Integrated Systems Biology Identifies Disruptions in Mitochondrial Function and Metabolism as Key Contributors to HFpEF

整合系统生物学指出，线粒体功能和代谢紊乱是导致射血分数保留型心力衰竭 (HFpEF) 的关键因素。

期刊:Jacc-Basic To Translational Science

影响因子:8.4

doi:10.1016/j.jacbts.2025.101334

Andrew A Gibb ,Kyle LaPenna ,Ryan B Gaspar ,Nadina R Latchman ,Yinfei Tan ,Carmen Choya-Foces ,Jake E Doiron ,Zhen Li ,Huijing Xia ,Michael P Lazaropoulos ,Mariell Conwell ,Thomas E Sharp 3rd ,Traci T Goodchild ,David J Lefer ,John W Elrod

发表日期：2025

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Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF

运动疗法可缓解心脏代谢性 HFpEF 患者的骨骼肌功能障碍和运动不耐受

期刊:Jacc-Basic To Translational Science

影响因子:8.4

doi:10.1016/j.jacbts.2024.07.009

Heather Quiriarte, Robert C Noland, James E Stampley, Gregory Davis, Zhen Li, Eunhan Cho, Youyoung Kim, Jake Doiron, Guillaume Spielmann, Sujoy Ghosh, Sanjiv J Shah, Brian A Irving, David J Lefer, Timothy D Allerton

发表日期：2024

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Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction

对于射血分数保留的心脏代谢性心力衰竭患者，口服 H2S 供体的辅助治疗可提供比 SGLT2 抑制更多的治疗益处

期刊:British Journal of Pharmacology

影响因子:6.8

doi:10.1111/bph.16493

Jake E Doiron, Huijing Xia, Xiaoman Yu, Alexandra R Nevins, Kyle B LaPenna, Thomas E Sharp 3rd, Traci T Goodchild, Timothy D Allerton, Mona Elgazzaz, Eric Lazartigues, Sanjiv J Shah, Zhen Li, David J Lefer

发表日期：2024

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Early Renal Denervation Attenuates Cardiac Dysfunction in Heart Failure With Preserved Ejection Fraction

早期肾脏去神经支配可减轻射血分数保留型心力衰竭患者的心脏功能障碍

期刊:Journal of the American Heart Association

doi:10.1161/JAHA.123.032646

Jake E Doiron,Zhen Li,Xiaoman Yu,Kyle B LaPenna,Heather Quiriarte,Timothy D Allerton,Kashyap Koul,Andrew Malek,Sanjiv J Shah,Thomas E Sharp,Traci T Goodchild,Daniel R Kapusta,David J Lefer

发表日期：2024

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Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high-fat diet

尼古丁吸入和高脂饮食联合暴露引起的心血管功能障碍

期刊:American Journal of Physiology-Heart and Circulatory Physiology

影响因子:4.1

doi:10.1152/ajpheart.00474.2023

Anna K Whitehead, Zhen Li, Kyle B LaPenna, Nour Abbes, Thomas E Sharp, David J Lefer, Eric Lazartigues, Xinping Yue

发表日期：2024

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Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF)

综合系统生物学发现，线粒体功能和代谢紊乱是射血分数保留型心力衰竭 (HFpEF) 的主要诱因

doi:10.1101/2024.10.25.619450

Andrew A Gibb, Kyle LaPenna, Ryan B Gaspar, Nadina R Latchman, Yinfei Tan, Carmen Choya-Foces, Jake E Doiron, Zhen Li, Huijing Xia, Michael P Lazaropoulos, Mariell Conwell, Thomas E Sharp 3rd, Traci T Goodchild, David J Lefer, John W Elrod

发表日期：2024

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Rapid onset fibrotic remodeling and ventricular dysfunction induced by phenylephrine involve targeted reprogramming of myocyte and fibroblast transcriptomes

苯肾上腺素诱发的快速纤维化重塑和心室功能障碍涉及肌细胞和成纤维细胞转录组的靶向重编程

doi:10.1101/2024.10.11.617933

Todd H Kimball, Tatiana Gromova, Natalie D Gehred, Douglas J Chapski, Ke Wang, Marmar Vaseghi, Matthew A Fischer, David J Lefer, Thomas M Vondriska

细胞生物学

成纤维细胞

发表日期：2024

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Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction

Alpha7 烟碱乙酰胆碱受体介导慢性尼古丁吸入引起的心肺功能障碍

期刊:Clinical Science

doi:10.1042/CS20220083

Anna K Whitehead #, Nicholas D Fried #, Zhen Li, Kandasamy Neelamegam, Charlotte S Pearson, Kyle B LaPenna, Thomas E Sharp, David J Lefer, Eric Lazartigues, Jason D Gardner, Xinping Yue

发表日期：2022

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Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

3-巯基丙酮酸硫转移酶缺乏小鼠的心血管表型

期刊:Biochemical Pharmacology

影响因子:5.3

doi:10.1016/j.bcp.2020.113833

Maria Peleli, Sofia-Iris Bibli, Zhen Li, Athanasia Chatzianastasiou, Aimilia Varela, Antonia Katsouda, Sven Zukunft, Mariarosaria Bucci, Valentina Vellecco, Constantinos H Davos, Noriyuki Nagahara, Giuseppe Cirino, Ingrid Fleming, David J Lefer, Andreas Papapetropoulos

发表日期：2020

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Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

内皮细胞胱硫醚γ-裂解酶表达水平调节运动能力、血管功能和心肌缺血再灌注损伤

期刊:Journal of the American Heart Association

doi:10.1161/JAHA.120.017544

Huijing Xia, Zhen Li, Thomas E Sharp 3rd, David J Polhemus, Jean Carnal, Karl H Moles, Ya-Xiong Tao, John Elrod, Josef Pfeilschifter, Karl-Friedrich Beck, David J Lefer

细胞生物学

发表日期：2020

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