David L Digiusto相关文献与解析，生知库 | 链接生命科学的每一步

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

ZFN 介导的人类造血干细胞/祖细胞 CCR5 破坏的临床前开发和鉴定

期刊:Molecular Therapy-Methods & Clinical Development

doi:10.1038/mtm.2016.67

David L DiGiusto, Paula M Cannon, Michael C Holmes, Lijing Li, Anitha Rao, Jianbin Wang, Gary Lee, Philip D Gregory, Kenneth A Kim, Samuel B Hayward, Kathleen Meyer, Colin Exline, Evan Lopez, Jill Henley, Nancy Gonzalez, Victoria Bedell, Rodica Stan, John A Zaia

Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMT(P140K) drug resistance gene

用于 HIV 基因治疗的优化慢病毒载体：小 RNA 的多重表达和 MGMT（P140K）耐药基因的纳入

期刊:Molecular Therapy

影响因子:12.1

doi:10.1038/mt.2014.32

Janet Chung, Lisa J Scherer, Angel Gu, Agnes M Gardner, Monica Torres-Coronado, Elizabeth W Epps, David L Digiusto, John J Rossi

Enhanced genetic modification of adult growth factor mobilized peripheral blood hematopoietic stem and progenitor cells with rapamycin

雷帕霉素增强了成人生长因子的基因修饰，动员了外周血造血干细胞和祖细胞。

期刊:Stem Cells Translational Medicine

影响因子:5.4

doi:10.5966/sctm.2014-0010

Lijing Li ，Mónica Torres-Coronado ，Angel Gu ，Anitha Rao ，Agnes M Gardner ，Elizabeth W Epps ，Nancy Gonzalez ，Chy-Anh Tran ，Xiwei Wu ，Jin-Hui Wang ，David L DiGiusto

Engraftment and lineage potential of adult hematopoietic stem and progenitor cells is compromised following short-term culture in the presence of an aryl hydrocarbon receptor antagonist

在芳烃受体拮抗剂存在下进行短期培养会损害成人造血干细胞和祖细胞的植入和谱系潜能

期刊:Human Gene Therapy Methods

影响因子:

doi:10.1089/hgtb.2014.043

Angel Gu, Monica Torres-Coronado, Chy-Anh Tran, Hieu Vu, Elizabeth W Epps, Janet Chung, Nancy Gonzalez, Suzette Blanchard, David L DiGiusto

Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

使用锌指核酸酶对成人造血干细胞和祖细胞中的 HIV-1 辅助受体 CCR5 进行基因组编辑

期刊:Molecular Therapy

影响因子:12.1

doi:10.1038/mt.2013.65

Lijing Li, Ludmila Krymskaya, Jianbin Wang, Jill Henley, Anitha Rao, Lan-Feng Cao, Chy-Anh Tran, Monica Torres-Coronado, Agnes Gardner, Nancy Gonzalez, Kenneth Kim, Pei-Qi Liu, Ursula Hofer, Evan Lopez, Philip D Gregory, Qing Liu, Michael C Holmes, Paula M Cannon, John A Zaia, David L DiGiusto

Current translational and clinical practices in hematopoietic cell and gene therapy

造血细胞和基因治疗的当前转化和临床实践

期刊:Cytotherapy

影响因子:3.7

doi:10.3109/14653249.2012.694420

David L Digiusto, Hans-Peter Kiem

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

使用慢病毒载体修饰的 CD34(+) 细胞对接受移植的艾滋病相关淋巴瘤患者进行基于 RNA 的 HIV 基因治疗

期刊:Science Translational Medicine

影响因子:15.8

doi:10.1126/scitranslmed.3000931

David L DiGiusto, Amrita Krishnan, Lijing Li, Haitang Li, Shirley Li, Anitha Rao, Shu Mi, Priscilla Yam, Sherri Stinson, Michael Kalos, Joseph Alvarnas, Simon F Lacey, Jiing-Kuan Yee, Mingjie Li, Larry Couture, David Hsu, Stephen J Forman, John J Rossi, John A Zaia

Detection of Replication Competent Lentivirus Using a qPCR Assay for VSV-G

使用 qPCR 检测 VSV-G 复制型慢病毒

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

ZFN 介导的人类造血干细胞/祖细胞 CCR5 破坏的临床前开发和鉴定

Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMT(P140K) drug resistance gene

用于 HIV 基因治疗的优化慢病毒载体：小 RNA 的多重表达和 MGMT（P140K）耐药基因的纳入

Enhanced genetic modification of adult growth factor mobilized peripheral blood hematopoietic stem and progenitor cells with rapamycin

雷帕霉素增强了成人生长因子的基因修饰，动员了外周血造血干细胞和祖细胞。

Engraftment and lineage potential of adult hematopoietic stem and progenitor cells is compromised following short-term culture in the presence of an aryl hydrocarbon receptor antagonist

在芳烃受体拮抗剂存在下进行短期培养会损害成人造血干细胞和祖细胞的植入和谱系潜能

Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

使用锌指核酸酶对成人造血干细胞和祖细胞中的 HIV-1 辅助受体 CCR5 进行基因组编辑

Current translational and clinical practices in hematopoietic cell and gene therapy

造血细胞和基因治疗的当前转化和临床实践

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

使用慢病毒载体修饰的 CD34(+) 细胞对接受移植的艾滋病相关淋巴瘤患者进行基于 RNA 的 HIV 基因治疗