Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A
针对纤溶酶原的脂质纳米颗粒和 siRNA 可在小鼠和狗血友病 A 模型中持久抑制纤维蛋白溶解
期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.adh0027
Amy W Strilchuk, Woosuk S Hur, Paul Batty, Yaqiu Sang, Sara R Abrahams, Alyssa S M Yong, Jerry Leung, Lakmali M Silva, Jocelyn A Schroeder, Kate Nesbitt, Bas de Laat, Niki M Moutsopoulos, Thomas H Bugge, Qizhen Shi, Pieter R Cullis, Elizabeth P Merricks, Alisa S Wolberg, Matthew J Flick, David Lilli
