David M Findlay相关文献与解析，生知库 | 链接生命科学的每一步

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma

缺氧激活前药evofosfamide与促凋亡受体激动剂联合使用可增强对骨肉瘤的抗癌作用

Vasilios Liapis, Aneta Zysk, Mark DeNichilo, Irene Zinonos, Shelley Hay, Vasilios Panagopoulos, Alexandra Shoubridge, Christopher Difelice, Vladimir Ponomarev, Wendy Ingman, Gerald J Atkins, David M Findlay, Andrew C W Zannettino, Andreas Evdokiou

信号转导

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer

药物抑制骨吸收可预防癌症引起的骨溶解，但会增强溶骨性乳腺癌小鼠模型中的软组织转移

期刊:International Journal of Oncology

影响因子:4.5

doi:10.3892/ijo.2014.2468

Irene Zinonos, Ke-Wang Luo, Agatha Labrinidis, Vasilios Liapis, Shelley Hay, Vasilios Panagopoulos, Mark Denichilo, Chun-Hay Ko, Grace Gar-Lee Yue, Clara Bik-San Lau, Wendy Ingman, Vladimir Ponomarev, Gerald J Atkins, David M Findlay, Andrew C W Zannettino, Andreas Evdokiou

Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2

硬化蛋白通过诱导碳酸酐酶 2 来调节骨细胞释放骨矿物质

期刊:Journal of Bone and Mineral Research

影响因子:5.1

doi:10.1002/jbmr.2003

Masakazu Kogawa, Asiri R Wijenayaka, Renee T Ormsby, Gethin P Thomas, Paul H Anderson, Lynda F Bonewald, David M Findlay, Gerald J Atkins

Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo

在体内存在高浓度且具有生物活性的骨保护素的情况下，Apo2L/TRAIL 的抗癌功效得以保留

期刊:Journal of Bone and Mineral Research

影响因子:5.1

doi:10.1002/jbmr.244

Irene Zinonos, Agatha Labrinidis, Michelle Lee, Vasilios Liapis, Shelley Hay, Vladimir Ponomarev, Peter Diamond, David M Findlay, Andrew C W Zannettino, Andreas Evdokiou

肿瘤

发表日期：2011

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TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

TWEAK 和 Fn14 表达在类风湿关节炎关节炎症和骨质侵蚀发病机制中的作用

期刊:Arthritis Research & Therapy

影响因子:4.4

doi:10.1186/ar3294

Anak A S S K Dharmapatni, Malcolm D Smith, Tania N Crotti, Christopher A Holding, Cristina Vincent, Helen M Weedon, Andrew C W Zannettino, Timothy S Zheng, David M Findlay, Gerald J Atkins, David R Haynes

Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

硬化蛋白通过 RANKL 依赖性途径刺激骨细胞支持破骨细胞活性

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0025900

Asiri R Wijenayaka, Masakazu Kogawa, Hui Peng Lim, Lynda F Bonewald, David M Findlay, Gerald J Atkins

Apo2L/TRAIL inhibits tumor growth and bone destruction in a murine model of multiple myeloma

Apo2L/TRAIL 抑制小鼠多发性骨髓瘤模型中的肿瘤生长和骨质破坏

期刊:Clinical Cancer Research

影响因子:10

doi:10.1158/1078-0432.CCR-08-2444

Agatha Labrinidis, Peter Diamond, Sally Martin, Shelley Hay, Vasilios Liapis, Irene Zinonos, Natalie A Sims, Gerald J Atkins, Cristina Vincent, Vladimir Ponomarev, David M Findlay, Andrew C W Zannettino, Andreas Evdokiou

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

caspase-3 抑制剂、survivin 和 xIAP 表达升高与活动性类风湿滑膜中细胞凋亡水平低相关

期刊:Arthritis Research & Therapy

影响因子:4.4

doi:10.1186/ar2603

Anak A S S K Dharmapatni, Malcolm D Smith, David M Findlay, Christopher A Holding, Andreas Evdokiou, Michael J Ahern, Helen Weedon, Paul Chen, Gavin Screaton, Xiao N Xu, David R Haynes

Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes

对金黄色葡萄球菌深骨感染的新见解：骨细胞的参与

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma

缺氧激活前药evofosfamide与促凋亡受体激动剂联合使用可增强对骨肉瘤的抗癌作用

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer

药物抑制骨吸收可预防癌症引起的骨溶解，但会增强溶骨性乳腺癌小鼠模型中的软组织转移

Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2

硬化蛋白通过诱导碳酸酐酶 2 来调节骨细胞释放骨矿物质

Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo

在体内存在高浓度且具有生物活性的骨保护素的情况下，Apo2L/TRAIL 的抗癌功效得以保留

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

TWEAK 和 Fn14 表达在类风湿关节炎关节炎症和骨质侵蚀发病机制中的作用

Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

硬化蛋白通过 RANKL 依赖性途径刺激骨细胞支持破骨细胞活性

Apo2L/TRAIL inhibits tumor growth and bone destruction in a murine model of multiple myeloma

Apo2L/TRAIL 抑制小鼠多发性骨髓瘤模型中的肿瘤生长和骨质破坏

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

caspase-3 抑制剂、survivin 和 xIAP 表达升高与活动性类风湿滑膜中细胞凋亡水平低相关