日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neuronal miR-9 promotes HSV-1 epigenetic silencing and latency by repressing Oct-1 and Onecut family genes

神经元 miR-9 通过抑制 Oct-1 和 Onecut 家族基因促进 HSV-1 表观遗传沉默和潜伏期

Yue Deng, Yuqi Lin, Siyu Chen, Yuhang Xiang, Hongjia Chen, Shuyuan Qi, Hyung Suk Oh, Biswajit Das, Gloria Komazin-Meredith, Jean M Pesola, David M Knipe, Donald M Coen, Dongli Pan

Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases

单纯疱疹病毒1型感染人脑类器官和胰岛干细胞可驱动与阿尔茨海默病和自身免疫性疾病相关的类器官特异性转录本的表达

Sundstrom, Jonathan; Vanderleeden, Emma; Barton, Nathaniel J; Redick, Sambra D; Dawes, Pepper; Murray, Liam F; Olson, Meagan N; Tran, Khanh; Chigas, Samantha M; Orszulak, Adrian R; Church, George M; Readhead, Benjamin; Oh, Hyung Suk; Harlan, David M; Knipe, David M; Wang, Jennifer P; Chan, Yingleong; Lim, Elaine T

Sp1 facilitates continued HSV-1 gene expression in the absence of key viral transactivators

在没有关键病毒转录激活因子的情况下,Sp1 促进 HSV-1 基因持续表达

Catherine N Sodroski, Hyung Suk Oh, Shu-Fan Chou, David M Knipe

IFNγ is a central node of cancer immune equilibrium

IFNγ是癌症免疫平衡的核心节点

Michael J Walsh ,Courtney T Stump ,Rakeeb Kureshi ,Patrick Lenehan ,Lestat R Ali ,Michael Dougan ,David M Knipe ,Stephanie K Dougan

Herpes simplex virus infected cell protein 8 is required for viral inhibition of the cGAS pathway

单纯疱疹病毒感染细胞蛋白 8 是病毒抑制 cGAS 通路所必需的

Nicole Broekema, Max E Mertens, Magdalena Angelova, Megan H Orzalli, Hyung S Oh, David M Knipe

Nuclear interferon-stimulated gene product maintains heterochromatin on the herpes simplex viral genome to limit lytic infection

核干扰素刺激基因产物维持单纯疱疹病毒基因组上的异染色质,以限制溶解性感染

Catherine N Sodroski, David M Knipe

The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity

单纯疱疹病毒的 US3 激酶磷酸化 RNA 传感器 RIG-I,从而抑制先天免疫

Michiel van Gent #, Jessica J Chiang #, Santoshi Muppala, Cindy Chiang, Walid Azab, Lisa Kattenhorn, David M Knipe, Nikolaus Osterrieder, Michaela U Gack

Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency

神经元 miR-138 对宿主和病毒基因的调控有利于单纯疱疹病毒 1 型的潜伏期

Boqiang Sun #, Xuewei Yang #, Fujun Hou #, Xiaofeng Yu, Qiongyan Wang, Hyung Suk Oh, Priya Raja, Jean M Pesola, Emilia A H Vanni, Seamus McCarron, Jenna Morris-Love, Alex H M Ng, George M Church, David M Knipe, Donald M Coen, Dongli Pan

Tissue-Resident-Memory CD8+ T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes

组织驻留记忆性 CD8+ T 细胞连接邻近上皮细胞的固有免疫反应,从而控制人类生殖器疱疹

Tao Peng ,Khamsone Phasouk ,Catherine N Sodroski ,Sijie Sun ,Yon Hwangbo ,Erik D Layton ,Lei Jin ,Alexis Klock ,Kurt Diem ,Amalia S Magaret ,Lichen Jing ,Kerry Laing ,Alvason Li ,Meei-Li Huang ,Max Mertens ,Christine Johnston ,Keith R Jerome ,David M Koelle ,Anna Wald ,David M Knipe ,Lawrence Corey ,Jia Zhu

ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection

ATRX 限制了组蛋白 H3 占据的 HSV 基因组在溶解性感染过程中的可及性

Joseph M Cabral, Camille H Cushman, Catherine N Sodroski, David M Knipe