日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiple Myeloma Derived Extracellular Vesicle Uptake by Monocyte Cells Stimulates IL-6 and MMP-9 Secretion and Promotes Cancer Cell Migration and Proliferation

单核细胞摄取多发性骨髓瘤衍生的细胞外囊泡可刺激 IL-6 和 MMP-9 分泌并促进癌细胞迁移和增殖

Rebecca Sheridan, Kieran Brennan, Despina Bazou, Peter O'Gorman, David Matallanas, Margaret M Mc Gee

Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis

Septin 2 的 Cyclophilin A 异构化介导胞质分裂过程中的脱落

Rebecca L Gorry, Kieran Brennan, Paul T M Lavin, Tayler Mazurski, Charline Mary, David Matallanas, Jean-François Guichou, Margaret M Mc Gee

Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes

麦角内酯介导对转移性葡萄膜黑色素瘤细胞的抗癌作用并调节其细胞和细胞外囊泡蛋白质组

Husvinee Sundaramurthi, Valentina Tonelotto, Kieran Wynne, Fiona O'Connell, Eve O'Reilly, Marcel Costa-Garcia, Csenger Kovácsházi, Agnes Kittel, Simone Marcone, Alfonso Blanco, Eva Pallinger, Szabolcs Hambalkó, Jose Maria Piulats Rodriguez, Péter Ferdinandy, Jacintha O'Sullivan, David Matallanas, La

Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib

KRAS 突变体相互作用组的蛋白质组学图谱鉴定出 RAS 信号网络的新特征以及 Sotorasib 的作用机制

Aoife Nolan, Cinzia Raso, Walter Kolch, Alex von Kriegsheim, Kieran Wynne, David Matallanas

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

LATS1 与 SMAC 的相互作用以 IAP 依赖的方式将 MST2/Hippo 通路与细胞凋亡联系起来

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma

蛋白酶体下调促凋亡 MST2 通路导致黑色素瘤对 BRAF 抑制剂产生耐药性

David Romano, Lucía García-Gutiérrez, Nourhan Aboud, David J Duffy, Keith T Flaherty, Dennie T Frederick, Walter Kolch, David Matallanas

BAX and SMAC regulate bistable properties of the apoptotic caspase system

BAX 和 SMAC 调节凋亡 caspase 系统的双稳态特性

Stephanie McKenna, Lucía García-Gutiérrez, David Matallanas, Dirk Fey

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

表达转化水平 KRASG13D 的结肠直肠癌细胞中 EGFR 网络发生广泛重组

Susan A Kennedy #, Mohamed-Ali Jarboui #, Sriganesh Srihari #, Cinzia Raso #, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBiha

Genes expression profiling of alveolar macrophages exposed to non-functionalized, anionic and cationic multi-walled carbon nanotubes shows three different mechanisms of toxicity

对暴露于非功能化、阴离子和阳离子多壁碳纳米管的肺泡巨噬细胞进行基因表达谱分析,结果显示存在三种不同的毒性机制。

Sara Nahle ,Hilary Cassidy ,Mélanie M Leroux ,Reuben Mercier ,Jaafar Ghanbaja ,Zahra Doumandji ,David Matallanas ,Bertrand H Rihn ,Olivier Joubert ,Luc Ferrari

Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis

细胞外囊泡增多介导囊性纤维化中的炎症信号传导

Zivile Useckaite, Mark P Ward, Anne Trappe, Rebecca Reilly, Jenny Lennon, Holly Davage, David Matallanas, Hilary Cassidy, Eugene T Dillon, Kiva Brennan, Sarah L Doyle, Suzanne Carter, Seamas Donnelly, Barry Linnane, Edward F McKone, Paul McNally, Judith A Coppinger