日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tumour tissue-derived small extracellular vesicles reflect molecular subtypes of bladder cancer

肿瘤组织来源的小细胞外囊泡反映膀胱癌的分子亚型

Liang Dong, Mingxiao Feng, Morgan D Kuczler, Kengo Horie, Chi-Ju Kim, Zehua Ma, Kara Lombardo, Heather Lyons, Sarah R Amend, Max Kates, Trinity J Bivalacqua, David McConkey, Wei Xue, Woonyoung Choi, Kenneth J Pienta

YAP1 induces bladder cancer progression and promotes immune evasion through IL-6/STAT3 pathway and CXCL deregulation

YAP1通过IL-6/STAT3通路和CXCL失调诱导膀胱癌进展并促进免疫逃逸

Pritam Sadhukhan ,Mingxiao Feng ,Emily Illingworth ,Ido Sloma ,Akira Ooki ,Andres Matoso ,David Sidransky ,Burles A Johnson 3rd ,Luigi Marchionni ,Fenna Cm Sillé ,Woonyoung Choi ,David McConkey ,Mohammad O Hoque

Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis

LPAR6 和 CAB39L 的缺失导致基底至腔内尿路上皮分化程序失调,从而导致膀胱癌

Sangkyou Lee, Jolanta Bondaruk, Yishan Wang, Huiqin Chen, June Goo Lee, Tadeusz Majewski, Rachel D Mullen, David Cogdell, Jiansong Chen, Ziqiao Wang, Hui Yao, Pawel Kus, Joon Jeong, Ilkyun Lee, Woonyoung Choi, Neema Navai, Charles Guo, Colin Dinney, Keith Baggerly, Cathy Mendelsohn, David McConkey, 

Inferring Bladder Cancer Evolution from Mucosal field Effects by Whole-Organ Spatial Mutational, Proteomic, and Metabolomic Mapping

通过全器官空间突变、蛋白质组学和代谢组学映射从粘膜场效应推断膀胱癌的演变

Bogdan Czerniak, Sangkyou Lee, Sung Yun Jung, Pawel Kus, Jolanta Bondaruk, June Lee, Roman Jaksik, Nagireddy Putluri, Khanh Dinh, David Cogdell, Huiqin Chen, Yishan Wang, Jiansong Chen, Neema Nevai, Colin Dinney, Cathy Mendelsohn, David McConkey, Richard Behringer, Charles Guo, Peng Wei, Marek Kimme

Combined Mek inhibition and Pparg activation Eradicates Muscle Invasive Bladder cancer in a Mouse Model of BBN-induced Carcinogenesis

联合抑制 Mek 和激活 Pparg 可消除 BBN 诱发的致癌小鼠模型中的肌肉浸润性膀胱癌

Tiffany Tate, Sakina A Plumber, Hikmat Al-Ahmadie, Xiao Chen, Woonyoung Choi, Chao Lu, Aaron Viny, Ekatherina Batourina, Krisjian Gartensson, Besmira Alija, Andrei Molotkov, Gregory Wiessner, James McKiernan, David McConkey, Colin Dinney, Bogdan Czerniak, Cathy Lee Mendelsohn

Improved bladder cancer antitumor efficacy with a recombinant BCG that releases a STING agonist

利用释放 STING 激动剂的重组 BCG 提高膀胱癌抗肿瘤疗效

Peter K Um, Monali Praharaj, Kara A Lombardo, Takahiro Yoshida, Andres Matoso, Alex S Baras, Liang Zhao, Geetha Srikrishna, Joy Huang, Pankaj Prasad, Max Kates, David McConkey, Drew M Pardoll, William R Bishai, Trinity J Bivalacqua

Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer

经过改造、过表达环状二磷酸腺苷(c-di-AMP)的卡介苗可增强训练免疫力,并提高对膀胱癌的疗效。

Alok Kumar Singh ,Monali Praharaj ,Kara A Lombardo ,Takahiro Yoshida ,Andres Matoso ,Alex S Baras ,Liang Zhao ,Geetha Srikrishna ,Joy Huang ,Pankaj Prasad ,Jonathan D Powell ,Max Kates ,David McConkey ,Drew M Pardoll ,William R Bishai ,Trinity J Bivalacqua

BCG invokes superior STING-mediated innate immune response over radiotherapy in a carcinogen murine model of urothelial cancer

在致癌物小鼠尿路上皮癌模型中,BCG 比放射疗法更能激发 STING 介导的先天免疫反应

Kara A Lombardo, Aleksandar Obradovic #, Alok Kumar Singh #, James L Liu, Gregory Joice, Max Kates, William Bishai, David McConkey, Alcides Chaux, Marie-Lisa Eich, M Katayoon Rezaei, George J Netto, Charles G Drake, Phuoc Tran, Andres Matoso, Trinity J Bivalacqua

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

通过靶向 I 型干扰素介导的免疫激活抑制尿路上皮癌

Devin Plote, Woonyoung Choi, Sharada Mokkapati, Debasish Sundi, James E Ferguson 3rd, Jon Duplisea, Nigel R Parker, Seppo Yla-Herttuala, Suo Ctc Bladder Committee, David McConkey, Kimberly S Schluns, Colin P Dinney

Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis

采用原位模型研究上皮-间质转化在膀胱癌转移中的作用

Beat Roth, Isuru Jayaratna, Debasish Sundi, Tiewei Cheng, Jonathan Melquist, Woonyoung Choi, Sima Porten, Giovanni Nitti, Neema Navai, Matthew Wszolek, Charles Guo, Bogdan Czerniak, David McConkey, Colin Dinney