David Penton相关文献与解析，生知库 | 链接生命科学的每一步

Matthew C S Denley,Monique S Straub,Giulio Marcionelli,Miriam A Güra,David Penton,Igor Delvendahl,Martin Poms,Beata Vekeriotaite,Sarah Cherkaoui,Federica Conte,Ferdinand von Meyenn,D Sean Froese,Matthias R Baumgartner

神经科学

线粒体

发表日期：2025

文献求助收藏

High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity

利用高通量筛选具有强效抗胶质母细胞瘤活性的可再利用神经活性药物

期刊:Nature Medicine

影响因子:58.7

doi:10.1038/s41591-024-03224-y

Sohyon Lee # ，Tobias Weiss # ，Marcel Bühler ，Julien Mena ，Zuzanna Lottenbach ，Rebekka Wegmann ，Miaomiao Sun ，Michel Bihl ，Bartłomiej Augustynek ，Sven P Baumann ，Sandra Goetze ，Audrey van Drogen ，Patrick G A Pedrioli ，David Penton ，Yasmin Festl ，Alicia Buck ，Daniel Kirschenbaum ，Anna M Zeitlberger ，Marian C Neidert ，Flavio Vasella ，Elisabeth J Rushing ，Bernd Wollscheid ，Matthias A Hediger ，Michael Weller ，Berend Snijder

细胞生物学

发表日期：2024

文献求助收藏

Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure

巨噬细胞保留肾上腺内皮细胞的特化，以调节醛固酮的分泌和血压

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2024.114395

Zheng Fan, Mara Karakone, Shunmugam Nagarajan, Nadine Nagy, Wiebke Mildenberger, Ekaterina Petrova, Laura Catharina Hinte, Mitchell Bijnen, Philipp Häne, Eric Nelius, Jing Chen, Irina Ferapontova, Ferdinand von Meyenn, Francesco Trepiccione, Mesut Berber, David Penton Ribas, Anne Eichmann, Maria-Chr

Zona Glomerulosa-Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice

球状带衍生的 Klotho 调节雌性小鼠醛固酮合酶的表达

期刊:Endocrinology

影响因子:3.8

doi:10.1210/endocr/bqae040

Arezoo Daryadel, Cong Tang, Ye Xie, Mirko Peitzsch, Viktoria Fisi, Constanze Hantel, Dominique Loffing-Cueni, David T Breault, David Penton, Johannes Loffing, Felix Beuschlein

信号转导

发表日期：2024

文献求助收藏

Calcineurin regulates aldosterone production via dephosphorylation of NFATC4

钙调神经磷酸酶通过 NFATC4 去磷酸化调节醛固酮的产生

期刊:JCI Insight

影响因子:6.3

doi:10.1172/jci.insight.157027

Mesut Berber, Sining Leng, Agnieszka Wengi, Denise V Winter, Alex Odermatt, Felix Beuschlein, Johannes Loffing, David T Breault, David Penton

A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma

对肾上腺皮质癌经典和新实验细胞模型中的类固醇生成信号的全面研究

期刊:Cells

影响因子:5.1

doi:10.3390/cells11091439

Sandra Sigala, Christina Bothou, David Penton, Andrea Abate, Mirko Peitzsch, Deborah Cosentini, Guido A M Tiberio, Stefan R Bornstein, Alfredo Berruti, Constanze Hantel

Spatial proteomics finds CD155 and Endophilin-A1 as mediators of growth and invasion in medulloblastoma

空间蛋白质组学发现 CD155 和 Endophilin-A1 是髓母细胞瘤生长和侵袭的介质

期刊:Life Science Alliance

影响因子:3.3

doi:10.26508/lsa.202201380

Charles Capdeville ，Linda Russo ，David Penton ，Jessica Migliavacca ，Milica Zecevic ，Alexandre Gries ，Stephan Cf Neuhauss ，Michael A Grotzer ，Martin Baumgartner

Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter

蛋白磷酸酶 1 抑制剂-1 介导肾脏 NaCl 共转运蛋白的 cAMP 依赖性刺激

期刊:Journal of the American Society of Nephrology

影响因子:10.3

doi:10.1681/ASN.2018050540

David Penton, Sandra Moser, Agnieszka Wengi, Jan Czogalla, Lena Lindtoft Rosenbaek, Fritz Rigendinger, Nourdine Faresse, Joana R Martins, Robert A Fenton, Dominique Loffing-Cueni, Johannes Loffing

Extracellular K+ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl- -dependent and independent mechanisms

细胞外 K+ 通过 Cl- 依赖性和非依赖性机制快速控制天然远曲小管中的 NaCl 同向转运蛋白磷酸化

期刊:Journal of Physiology-London

影响因子:2.1

doi:10.1113/JP272504

David Penton, Jan Czogalla, Agnieszka Wengi, Nina Himmerkus, Dominique Loffing-Cueni, Monique Carrel, Renuga Devi Rajaram, Olivier Staub, Markus Bleich, Frank Schweda, Johannes Loffing

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

ATP1A1 和 ATP2B3 的体细胞突变会导致产生醛固酮的腺瘤和继发性高血压

期刊:Nature Genetics

影响因子:31.7

doi:10.1038/ng.2550

Felix Beuschlein, Sheerazed Boulkroun, Andrea Osswald, Thomas Wieland, Hang N Nielsen, Urs D Lichtenauer, David Penton, Vivien R Schack, Laurence Amar, Evelyn Fischer, Anett Walther, Philipp Tauber, Thomas Schwarzmayr, Susanne Diener, Elisabeth Graf, Bruno Allolio, Benoit Samson-Couterie, Arndt Bene

Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduria

线粒体功能障碍导致甲基丙二酸尿症出现神经元衰竭表型

High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity

利用高通量筛选具有强效抗胶质母细胞瘤活性的可再利用神经活性药物

Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure

巨噬细胞保留肾上腺内皮细胞的特化，以调节醛固酮的分泌和血压

Zona Glomerulosa-Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice

球状带衍生的 Klotho 调节雌性小鼠醛固酮合酶的表达

Calcineurin regulates aldosterone production via dephosphorylation of NFATC4

钙调神经磷酸酶通过 NFATC4 去磷酸化调节醛固酮的产生

A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma

对肾上腺皮质癌经典和新实验细胞模型中的类固醇生成信号的全面研究

Spatial proteomics finds CD155 and Endophilin-A1 as mediators of growth and invasion in medulloblastoma

空间蛋白质组学发现 CD155 和 Endophilin-A1 是髓母细胞瘤生长和侵袭的介质

Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter

蛋白磷酸酶 1 抑制剂-1 介导肾脏 NaCl 共转运蛋白的 cAMP 依赖性刺激

Extracellular K+ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl- -dependent and independent mechanisms

细胞外 K+ 通过 Cl- 依赖性和非依赖性机制快速控制天然远曲小管中的 NaCl 同向转运蛋白磷酸化

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

ATP1A1 和 ATP2B3 的体细胞突变会导致产生醛固酮的腺瘤和继发性高血压