日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Superinfection promotes replication and diversification of defective HIV-1 proviruses in people with non-suppressible viraemia

超感染会促进病毒载量无法抑制的患者体内缺陷型 HIV-1 前病毒的复制和多样化。

Vivek Hariharan ,Jennifer A White ,Filippo Dragoni ,Emily J Fray ,Nicholas Pathoulas ,Milica Moskovljevic ,Hao Zhang ,Anushka Singhal ,Jun Lai ,Subul A Beg ,Eileen P Scully ,Elizabeth A Gilliams ,David S Block ,Jeanne Keruly ,Richard D Moore ,Janet D Siliciano ,Francesco R Simonetti ,Robert F Siliciano

Cleaning of anthropometric data from PCORnet electronic health records using automated algorithms

使用自动化算法清理来自 PCORnet 电子健康记录的人体测量数据

Lin, Pi-I D; Rifas-Shiman, Sheryl L; Aris, Izzuddin M; Daley, Matthew F; Janicke, David M; Heerman, William J; Chudnov, Daniel L; Freedman, David S; Block, Jason P

An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza

ACE2-IgG4 Fc 融合蛋白与所有经测试的 SARS-CoV-2 变体均表现出强结合力,并减轻了 SARS-CoV-2 和流感动物模型中的肺部炎症

Emmanuel Y Merigeon, Dong Yang, Elizabeth A Ihms, Leda C Bassit, Elizabeth A Fitzpatrick, Colleen B Jonsson, Raymond F Schinazi, David S Block, Henrik S Olsen

Cognitive and Emotional Mapping With SEEG

利用立体定向脑电图进行认知和情绪映射

Drane, Daniel L; Pedersen, Nigel P; Sabsevitz, David S; Block, Cady; Dickey, Adam S; Alwaki, Abdulrahman; Kheder, Ammar

A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity

一种重组人IgG1 Fc多聚体,旨在模拟静脉注射免疫球蛋白在自身免疫中的活性部分

Xiaoyu Zhang ,Jane Owens ,Henrik S Olsen ,Edward So ,Erin Burch ,Mark C McCroskey ,Xianfeng Li ,Gregory L Weber ,Donald Bennett ,Denis Rybin ,Hua Zhou ,Haiping Hao ,Emmanuel Y Mérigeon ,David S Block ,Gregory LaRosa ,Scott E Strome

Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease

重组人 IgG1 基 Fc 多聚体具有有限的 FcR 结合能力,可有效抑制补体介导的疾病

Haoping Sun, Henrik S Olsen, Emmanuel Y Mérigeon, Edward So, Erin Burch, Susan Kinsey, John C Papadimitriou, Cinthia B Drachenberg, Søren M Bentzen, David S Block, Scott E Strome, Xiaoyu Zhang

A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b

完全重组人 IgG1 Fc 多聚体 (GL-2045) 可抑制补体介导的细胞毒性并诱导 iC3b

Hua Zhou, Henrik Olsen, Edward So, Emmanuel Mérigeon, Denis Rybin, Jane Owens, Gregory LaRosa, David S Block, Scott E Strome, Xiaoyu Zhang

Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease

具有多聚化 Fc 结构域的抗 CD20 抗体:一种消耗 B 细胞并增强自身免疫性疾病治疗的新策略

Xiaoyu Zhang, Henrik S Olsen, Shaodong Chen, Edward So, Hua Zhou, Erin Burch, Emmanuel Y Mérigeon, David S Block, Scott E Strome

Fully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in mice

完全重组 IgG2a Fc 多聚体 (stradomers) 可有效治疗小鼠胶原诱导性关节炎并预防特发性血小板减少性紫癜

Ajay Jain, Henrik S Olsen, Ravi Vyzasatya, Erin Burch, Yukimi Sakoda, Emmanuel Y Mérigeon, Ling Cai, Changwan Lu, Ming Tan, Koji Tamada, Dan Schulze, David S Block, Scott E Strome