日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy

基于机器学习的文库设计中的最佳权衡控制及其在腺相关病毒 (AAV) 基因治疗中的应用

Danqing Zhu, David H Brookes, Akosua Busia, Ana Carneiro, Clara Fannjiang, Galina Popova, David Shin, Kevin C Donohue, Li F Lin, Zachary M Miller, Evan R Williams, Edward F Chang, Tomasz J Nowakowski, Jennifer Listgarten, David V Schaffer

Substrate stress relaxation regulates neural stem cell fate commitment

基质应力松弛调节神经干细胞命运决定

Eric Qiao, Camille A Fulmore, David V Schaffer, Sanjay Kumar

Optogenetic control of Wnt signaling models cell-intrinsic embryogenic patterning using 2D human pluripotent stem cell culture

利用二维人类多能干细胞培养,通过光遗传学控制 Wnt 信号模型建立细胞内在胚胎发生模式

Nicole A Repina, Hunter J Johnson, Xiaoping Bao, Joshua A Zimmermann, David A Joy, Shirley Z Bi, Ravi S Kane, David V Schaffer

Egr1 is a 3D matrix-specific mediator of mechanosensitive stem cell lineage commitment

Egr1 是一种 3D 基质特异性介质,可介导机械敏感干细胞谱系承诺

Jieung Baek, Paola A Lopez, Sangmin Lee, Taek-Soo Kim, Sanjay Kumar, David V Schaffer

A reductionist approach to determine the effect of cell-cell contact on human epidermal stem cell differentiation

采用还原论方法确定细胞间接触对人类表皮干细胞分化的影响

Blaise Louis, Mukul Tewary, Andrew W Bremer, Christina Philippeos, Victor A Negri, Sebastiaan Zijl, Zev J Gartner, David V Schaffer, Fiona M Watt

N-Cadherin adhesive ligation regulates mechanosensitive neural stem cell lineage commitment in 3D matrices

N-钙黏蛋白黏附连接调控三维基质中机械敏感性神经干细胞谱系分化

Jieung Baek ,Sanjay Kumar ,David V Schaffer ,Sung Gap Im

A scalable and tunable thermoreversible polymer for 3D human pluripotent stem cell biomanufacturing

用于 3D 人类多能干细胞生物制造的可扩展且可调节的热可逆聚合物

Hunter J Johnson, Saheli Chakraborty, Riya J Muckom, Nitash P Balsara, David V Schaffer

scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution

scAAVengr,一种基于转录组的流程,用于以单细胞分辨率对工程化 AAV 进行定量排序

Bilge E Öztürk, Molly E Johnson, Michael Kleyman, Serhan Turunç, Jing He, Sara Jabalameli, Zhouhuan Xi, Meike Visel, Valérie L Dufour, Simone Iwabe, Luis Felipe L Pompeo Marinho, Gustavo D Aguirre, José-Alain Sahel, David V Schaffer, Andreas R Pfenning, John G Flannery, William A Beltran, William R

Recapitulating complex biological signaling environments using a multiplexed, DNA-patterning approach

使用多路复用 DNA 模式方法重现复杂的生物信号环境

Olivia J Scheideler, Chun Yang, Molly Kozminsky, Kira I Mosher, Roberto Falcón-Banchs, Emma C Ciminelli, Andrew W Bremer, Sabrina A Chern, David V Schaffer, Lydia L Sohn

Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics

用于光遗传学控制细胞信号动力学的工程照明装置

Nicole A Repina, Thomas McClave, Hunter J Johnson, Xiaoping Bao, Ravi S Kane, David V Schaffer