日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity

小分子 LIMK1/2 抑制剂的比较分析:化学合成、生物化学和细胞活性

Ross Collins, Hyunah Lee, D Heulyn Jones, Jonathan M Elkins, Jason A Gillespie, Carys Thomas, Alex G Baldwin, Kimberley Jones, Loren Waters, Marie Paine, John R Atack, Simon E Ward, Olivera Grubisha, David W Foley

Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery

以肠道寡肽转运体为靶点的硫二肽是改善口服药物输送的通用方法

David W Foley, Ravindra B Pathak, Theresa R Phillips, Gayle L Wilson, Patrick D Bailey, Myrtani Pieri, Anish Senan, David Meredith

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies

预后不良的恶性肿瘤和类风湿性关节炎中的钙粘蛋白-11:共同靶点、共同疗法

Shahin Assefnia, Sivanesan Dakshanamurthy, Jaime M Guidry Auvil, Constanze Hampel, Panos Z Anastasiadis, Bhaskar Kallakury, Aykut Uren, David W Foley, Milton L Brown, Lawrence Shapiro, Michael Brenner, David Haigh, Stephen W Byers

Substituted 4-(thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure-activity relationship, and anticancer activities

取代的 4-(噻唑-5-基)-2-(苯氨基)嘧啶是高活性的 CDK9 抑制剂:合成、X 射线晶体结构、构效关系和抗癌活性

Hao Shao, Shenhua Shi, Shiliang Huang, Alison J Hole, Abdullahi Y Abbas, Sonja Baumli, Xiangrui Liu, Frankie Lam, David W Foley, Peter M Fischer, Martin Noble, Jane A Endicott, Chris Pepper, Shudong Wang