日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted disruption of the orphan receptor Gpr151 does not alter pain-related behaviour despite a strong induction in dorsal root ganglion expression in a model of neuropathic pain

尽管在神经性疼痛模型中强烈诱导背根神经节表达,但针对性地破坏孤儿受体 Gpr151 不会改变疼痛相关行为

Fiona E Holmes, Niall Kerr, Ying-Ju Chen, Penny Vanderplank, Craig A McArdle, David Wynick

VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro

VEGF-A165b 是体内和体外血管内皮生长因子 A 的内源性神经保护剪接异构体

Nicholas Beazley-Long, Jing Hua, Thomas Jehle, Richard P Hulse, Rick Dersch, Christina Lehrling, Heather Bevan, Yan Qiu, Wolf A Lagrèze, David Wynick, Amanda J Churchill, Patrick Kehoe, Steven J Harper, David O Bates, Lucy F Donaldson

Endogenous galanin protects mouse hippocampal neurons against amyloid toxicity in vitro via activation of galanin receptor-2

内源性甘丙肽通过激活甘丙肽受体 2 保护小鼠海马神经元免受体外淀粉样蛋白毒性

Caroline R Elliott-Hunt, Fiona E Holmes, Dean M Hartley, Sylvia Perez, Elliott J Mufson, David Wynick

Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour

神经内注射分形因子可减轻神经性疼痛相关行为

Fiona E Holmes, Nighat Arnott, Penny Vanderplank, Niall C H Kerr, Erin E Longbrake, Philip G Popovich, Toshio Imai, Christophe Combadière, Philip M Murphy, David Wynick

Activation of the galanin receptor 2 (GalR2) protects the hippocampus from neuronal damage

激活甘丙肽受体 2 (GalR2) 可保护海马免受神经元损伤

Caroline R Elliott-Hunt, Robert J P Pope, Penny Vanderplank, David Wynick

The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel

钠通道 Nav1.5a 是成年小鼠背根神经节中表达的主要亚型,与全长 Nav1.5 通道相比,具有不同的失活特性

Niall C H Kerr, Zhan Gao, Fiona E Holmes, Sally-Ann Hobson, Jules C Hancox, David Wynick, Andrew F James

Galanin acts as a neuroprotective factor to the hippocampus

甘丙肽作为海马体的神经保护因子

Caroline R Elliott-Hunt, Barnaby Marsh, Andrea Bacon, Robert Pope, Penny Vanderplank, David Wynick

The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons

第二种甘丙肽受体 GalR2 在成年感觉神经元的神经突生长中起着关键作用

Sally-Ann Mahoney, Richard Hosking, Sarah Farrant, Fiona E Holmes, Arie S Jacoby, John Shine, Tiina P Iismaa, Malcolm K Scott, Ralf Schmidt, David Wynick