日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Overlapping Yet Distinct Functions of Vacuole Membrane Protein 1 and Transmembrane Protein 41B in Modulating Hepatic Lipoprotein Secretion and Autophagy.

液泡膜蛋白 1 和跨膜蛋白 41B 在调节肝脏脂蛋白分泌和自噬中具有重叠但又不同的功能。

Chen Allen, Nguyen Khue, Niu Mengwei, Jiang Xiaoxiao, Yu Xiaochen, Xie Yan, Liu Wanqing, Davidson Nicholas O, Ding Wen-Xing, Ni Hong-Min

Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD

对特征明确的MASLD患者中与单基因血脂异常相关的致病变异进行评估

Schwantes-An, Tae-Hwi; Abreu, Marco A; Neuschwander-Tetri, Brent A; Wang, Jian; Guo, Xiuqing; Tan, Jingyi; Hegele, Robert A; Davidson, Nicholas O; Lotta, Luca; Verweij, Niek; Yates, Katherine P; Rotter, Jerome I; Chalasani, Naga

Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer

Apobec1互补因子过表达促进肝脂肪变性、纤维化和肝细胞癌的发生。

Blanc, Valerie; Riordan, Jesse D; Soleymanjahi, Saeed; Nadeau, Joseph H; Nalbantoglu, ILKe; Xie, Yan; Molitor, Elizabeth A; Madison, Blair B; Brunt, Elizabeth M; Mills, Jason C; Rubin, Deborah C; Ng, Irene O; Ha, Yeonjung; Roberts, Lewis R; Davidson, Nicholas O

Effect of complete, lifelong ANGPTL3 deficiency on triglyceride-rich lipoprotein kinetics.

终生 ANGPTL3 完全缺乏对富含甘油三酯的脂蛋白动力学的影响

Fappi Alan, Patterson Bruce W, Burks Kendal H, Davidson Nicholas O, Vaisar Tomas, Kanter Jenny E, Bornfeldt Karin E, Fisher Edward A, Goldberg Ira J, Stitziel Nathan O, Mittendorfer Bettina

Single Nuclear RNA Sequencing Reveals Unique Hepatocyte Population in Small Bowel Resection-induced Liver Injury

单核RNA测序揭示小肠切除术后肝损伤中独特的肝细胞群

Park, Alex; Alligood, Daniel M; Swanson, Kerry; Shi, Chunxiao; Guo, Jun; Davidson, Nicholas O; Rubin, Deborah R; Alvarado, David M; Warner, Brad W

Molecular Regulation and Therapeutic Targeting of VLDL Production in Cardiometabolic Disease

心血管代谢疾病中极低密度脂蛋白(VLDL)生成的分子调控和治疗靶向

Burks, Kendall H; Stitziel, Nathan O; Davidson, Nicholas O

Liver injury in a preclinical model of short bowel syndrome is associated with impaired autophagy

在短肠综合征的临床前模型中,肝损伤与自噬功能受损有关。

Alligood, Daniel M; Park, Alex; Swanson, Kerry; Pyarali, Naima; Mayse, Evan; Alvarado, David M; Liu, Xiuli; Kim, Jae-Sung; Davidson, Nicholas O; Rubin, Deborah C; Guo, Jun; Warner, Brad W

Tauroursodeoxycholic Acid (TUDCA) Reduces ER Stress and Lessens Disease Activity in Ulcerative Colitis

牛磺熊去氧胆酸 (TUDCA) 可减轻内质网应激并降低溃疡性结肠炎的疾病活动度

Lamm, Vladimir; Huang, Katherine; Deng, Ruishu; Cao, Siyan; Wang, Miao; Soleymanjahi, Saeed; Promlek, Thanyarat; Rodgers, Rachel; Davis, Deanna; Nix, Darren; Escudero, Guadalupe Oliva; Xie, Yan; Chen, Chien-Huan; Gremida, Anas; Rood, Richard P; Liu, Ta-Chiang; Baldridge, Megan T; Deepak, Parakkal; Davidson, Nicholas O; Kaufman, Randal J; Ciorba, Matthew A

IRE1α and IRE1β Protect Intestinal Epithelium and Suppress Colorectal Tumorigenesis through Distinct Mechanisms.

IRE1α 和 IRE1β 通过不同的机制保护肠道上皮并抑制结直肠肿瘤发生

Deng Ruishu, Wang Miao, Promlek Thanyarat, Druelle-Cedano Clementine, Murad Rabi, Davidson Nicholas O, Kaufman Randal J

Elevated apolipoprotein C3 heightens atherosclerosis risk by mediating arterial accumulation of free cholesterol and local inflammation in diabetes.

糖尿病患者体内载脂蛋白 C3 水平升高,通过介导动脉内游离胆固醇的积累和局部炎症,增加动脉粥样硬化的风险

Kanter Jenny E, Hsu Cheng-Chieh, Kramer Farah, Shao Baohai, Vaisar Tomas, den Hartigh Laura J, Reed Abigail, Luo Jason, Tran Alan, Tang Jingjing, Mangalapalli Henry, Cervantes Jocelyn, Shimizu-Albergine Masami, Reaven Peter D, Koska Juraj, Jensen Majken K, Davies Brandon S J, Fisher Edward A, Davidson Nicholas O, Stitziel Nathan O, Mullick Adam E, Goldberg Ira J, Bornfeldt Karin E