日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PRMT5-regulated splicing of DNA repair genes drives chemoresistance in breast cancer stem cells

PRMT5调控的DNA修复基因剪接驱动乳腺癌干细胞的化疗耐药性

Gillespie, Matthew S; Chiang, Kelly; Regan-Mochrie, Gemma L; Choi, Soo-Youn; Ward, Ciara M; Sahay, Debashish; Garcia, Paloma; Arnold, Roland; Davies, Clare C

Arginine methylation regulates Ewing sarcoma cell viability in a EWSR1::FLI1 dependent manner and provides a therapeutic opportunity.

精氨酸甲基化以 EWSR1::FLI1 依赖的方式调节尤文氏肉瘤细胞的活力,并提供了一种治疗机会

Ward Ciara M, Brockwell Charles, McNee Gavin S, Orton Emily, Prowse Emily N P, Gatz Susanne A, Davies Clare C

DNA Repair and Therapeutic Strategies in Cancer Stem Cells

癌症干细胞中的DNA修复和治疗策略

Gillespie, Matthew S; Ward, Ciara M; Davies, Clare C

Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease

利用 CRISPR/Cas9 基因组编辑技术构建小鼠肺癌模型,以展现人类疾病的突变图谱

Hartmann, Oliver; Reissland, Michaela; Maier, Carina R; Fischer, Thomas; Prieto-Garcia, Cristian; Baluapuri, Apoorva; Schwarz, Jessica; Schmitz, Werner; Garrido-Rodriguez, Martin; Pahor, Nikolett; Davies, Clare C; Bassermann, Florian; Orian, Amir; Wolf, Elmar; Schulze, Almut; Calzado, Marco A; Rosenfeldt, Mathias T; Diefenbacher, Markus E

Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4)

蛋白质精氨酸N-甲基转移酶PRMT1和CARM1(PRMT4)双底物抑制剂的结构和生化评价

Gunnell, Emma A; Al-Noori, Alaa; Muhsen, Usama; Davies, Clare C; Dowden, James; Dreveny, Ingrid

Linking PRMT5 to breast cancer stem cells: New therapeutic opportunities?

PRMT5与乳腺癌干细胞的关联:新的治疗契机?

Chiang, Kelly; Davies, Clare C

ERK5 is a critical mediator of inflammation-driven cancer

ERK5是炎症驱动癌症的关键介质。

Finegan, Katherine G; Perez-Madrigal, Diana; Hitchin, James R; Davies, Clare C; Jordan, Allan M; Tournier, Cathy

Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma

JNK信号通路受损与KrasG12D表达协同作用,加速胰腺导管腺癌的进展

Davies, Clare C; Harvey, Emma; McMahon, Raymond F T; Finegan, Katherine G; Connor, Frances; Davis, Roger J; Tuveson, David A; Tournier, Cathy