日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vivo imaging of glutamate uncovers the neuroprotective effects of nicotinamide riboside on excitotoxicity in an Alzheimer's mouse model

体内成像技术揭示了烟酰胺核苷对阿尔茨海默病小鼠模型中兴奋性毒性的神经保护作用。

Swain, Anshuman; Soni, Narayan Datt; Gaspar, Ryan B; Davis, James G; Liu, Fang; Juul, Halvor; Nanga, Ravi Prakash Reddy; Baur, Joseph A; Reddy, Ravinder

Hepatocyte mitochondrial NAD(+) content is limiting for liver regeneration.

肝细胞线粒体 NAD(+) 含量限制了肝脏再生。

Mukherjee Sarmistha, Velázquez Aponte Ricardo A, Perry Caroline E, Lee Won Dong, Janssen Kevin A, Niere Marc, Adzika Gabriel K, Lu Mu-Jie, Chan Hsin-Ru, Zou Xiangyu, Chen Beishan, Bye Nicole, Xiao Teresa, Yook Jin-Seon, Salik Oniel, Frederick David W, Gaspar Ryan B, Doan Khanh V, Davis James G, Rabinowitz Joshua D, Wallace Douglas C, Snyder Nathaniel W, Kajimura Shingo, Cambronne Xiaolu A, Ziegler Mathias, Baur Joseph A

Cardiac NAD(+) depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics

小鼠心脏中 NAD(+) 耗竭会促进肥厚型心肌病和心律失常,随后才会出现生物能量学障碍。

Doan, Khanh V; Luongo, Timothy S; Ts'olo, Thato T; Lee, Won Dong; Frederick, David W; Mukherjee, Sarmistha; Adzika, Gabriel K; Perry, Caroline E; Gaspar, Ryan B; Walker, Nicole; Blair, Megan C; Bye, Nicole; Davis, James G; Holman, Corey D; Chu, Qingwei; Wang, Lin; Rabinowitz, Joshua D; Kelly, Daniel P; Cappola, Thomas P; Margulies, Kenneth B; Baur, Joseph A

Optical Redox Imaging of Fixed Unstained Muscle Slides Reveals Useful Biological Information

对固定未染色肌肉切片进行光学氧化还原成像,揭示了有用的生物学信息

Xu, He N; Zhao, Huaqing; Chellappa, Karthikeyani; Davis, James G; Nioka, Shoko; Baur, Joseph A; Li, Lin Z

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.

NAD稳态丧失会导致骨骼肌进行性、可逆性退化

Frederick David W, Loro Emanuele, Liu Ling, Davila Antonio Jr, Chellappa Karthikeyani, Silverman Ian M, Quinn William J 3rd, Gosai Sager J, Tichy Elisia D, Davis James G, Mourkioti Foteini, Gregory Brian D, Dellinger Ryan W, Redpath Philip, Migaud Marie E, Nakamaru-Ogiso Eiko, Rabinowitz Joshua D, Khurana Tejvir S, Baur Joseph A

Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium

白藜芦醇用于动脉粥样硬化的一级预防:临床试验证据表明其可改善血管内皮细胞的基因表达。

Agarwal, Beamon; Campen, Matthew J; Channell, Meghan M; Wherry, Sarah J; Varamini, Behzad; Davis, James G; Baur, Joseph A; Smoliga, James M