日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti-CEACAM5 CAR T-Cell Efficacy Against Colorectal Cancer

肿瘤微环境的酶促重塑增强抗CEACAM5 CAR T细胞对结直肠癌的疗效

Banik, Debasis; Ward, Christopher J; Chakraborty, Soura; Zhang, Ziwei; Heraghty, Daniel; Suresh, Prasanna; Li, Bing; Kedia, Shekhar; Pramanik, Jhuma; Davis, Simon J; Roy, James P; Chapman, Michael A; Mahata, Bidesh; Klenerman, David

Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis.

允许的中枢耐受加上有缺陷的外周检查点使 CASPR2 抗体脑炎中的致病性记忆 B 细胞得以存活

Sun Bo, Fernandes Dominique, Soltys John, Kienzler Anne-Kathrin, Paneva Sofija, Harrison Ruby, Ramanathan Sudarshini, Harrison Anna L, Makuch Mateusz, Fichtner Miriam L, Donat Robert F, Akdeniz Deniz, Bayuangga Halwan, Im Min Gyu, Williams Robyn, Vasconcelos Ana, Thomsen Selina, Fower Andrew, Sun Ruyue, Fox Hannah, Mgbachi Victor, Davies Alexander, Tseng Mandy, Handel Adam, Kelly Mark, Zhao Meng, Bancroft James, Bashford-Rogers Rachael, Pluvinage John V, Dandekar Ravi, Alvarenga Bonny D, Dustin Lynn B, Rinaldi Simon, Owens Ray, Anthony Daniel, Bennett David L, Waters Patrick, Davis Simon J, Wilson Michael R, O'Connor Kevin C, Carvalho Ana Luisa, Irani Sarosh R

The Structural Biology of T-Cell Antigen Detection at Close Contacts

近距离接触中T细胞抗原检测的结构生物学

Lui, Yuan; Ferreira Fernandes, João; Vuong, Mai T; Sharma, Sumana; Santos, Ana Mafalda; Davis, Simon J

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

抗体激动剂通过局部排除受体型蛋白酪氨酸磷酸酶来触发免疫受体信号传导。

Lippert Anna H, Paluch Christopher, Gaglioni Meike, Vuong Mai T, McColl James, Jenkins Edward, Fellermeyer Martin, Clarke Joseph, Sharma Sumana, Moreira da Silva Sara, Akkaya Billur, Anzilotti Consuelo, Morgan Sara H, Jessup Claire F, Körbel Markus, Gileadi Uzi, Leitner Judith, Knox Rachel, Chirifu Mami, Huo Jiandong, Yu Susan, Ashman Nicole, Lui Yuan, Wilkinson Ian, Attfield Kathrine E, Fugger Lars, Robertson Nathan J, Lynch Christopher J, Murray Lynne, Steinberger Peter, Santos Ana Mafalda, Lee Steven F, Cornall Richard J, Klenerman David, Davis Simon J

The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling

CD6相互作用组协调配体非依赖性T细胞抑制信号传导

Santos, Rita F; de Sousa Linhares, Annika; Steinberger, Peter; Davis, Simon J; Oliveira, Liliana; Carmo, Alexandre M

Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis

实验性自身免疫性葡萄膜炎期间视网膜免疫调节和血视网膜屏障功能的单细胞转录组分析

Quinn, Joel; Salman, Ahmed; Paluch, Christopher; Jackson-Wood, Matthew; McClements, Michelle E; Luo, Jian; Davis, Simon J; Cornall, Richard J; MacLaren, Robert E; Dendrou, Calliope A; Xue, Kanmin

A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein

一种具有保护作用的多基因缺失的非洲猪瘟病毒II型基因型,Georgia 2007/1,表达一种修饰的非血吸附性CD2v蛋白。

Rathakrishnan, Anusyah; Reis, Ana L; Petrovan, Vlad; Goatley, Lynnette C; Moffat, Katy; Lui, Yuan; Vuong, Mai T; Ikemizu, Shinji; Davis, Simon J; Dixon, Linda K

The current state and future of T-cell exhaustion research

T细胞耗竭研究的现状与未来

Jenkins, Edward; Whitehead, Toby; Fellermeyer, Martin; Davis, Simon J; Sharma, Sumana

The kinase occupancy of T cell coreceptors reconsidered

重新审视T细胞共受体的激酶占有率

Mørch, Alexander M; Schneider, Falk; Jenkins, Edward; Santos, Ana Mafalda; Fraser, Scott E; Davis, Simon J; Dustin, Michael L

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling

在紧密接触处捕获或减缓T细胞受体的扩散会启动T细胞信号传导。

Chen, Kevin Y; Jenkins, Edward; Körbel, Markus; Ponjavic, Aleks; Lippert, Anna H; Santos, Ana Mafalda; Ashman, Nicole; O'Brien-Ball, Caitlin; McBride, Jemma; Klenerman, David; Davis, Simon J