日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A polygenetic rat model of divergent aerobic capacity reveals a liver-brain interaction impacting Alzheimer's disease-like phenotypes

具有不同有氧能力的多基因大鼠模型揭示了肝脑相互作用对阿尔茨海默病样表型的影响

Lysaker, Colton R; Kugler, Benjamin A; Csikos, Vivien; Birky, Cole J; Gilmore, Caleb A; Wenger, Madi; Franczak, Edziu; Davis, Xin; Hauger, Brittany M; Allen, Julie A; Troutwine, Benjamin R; Gonzalez-Duran, Laura; McCoin, Colin S; Chauhan, Munish; Harris, Janna L; Frazier, Alexandria L; Winter, Michelle K; Koch, Lauren G; Britton, Steven L; Thyfault, John P; Wilkins, Heather M

Hepatic ketogenic insufficiency blunts exercise-induced energy expenditure and alters mitochondrial proteins in skeletal muscle

肝脏生酮功能不足会减弱运动引起的能量消耗,并改变骨骼肌中的线粒体蛋白。

Davis, Xin C; McCoin, Colin S; Salathe, Sebastian F; Franczak, Edziu; Allen, Julie A; Queathem, Eric D; Fulghum, Kyle L; Puchalska, Patrycja; Crawford, Peter A; Thyfault, John P; Morris, E Matthew

Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis.

蛋白质组学和代谢组学分析揭示了 APOE4 依赖性的全脑、神经元和星形胶质细胞线粒体功能和糖酵解的变化

Lysaker Colton R, Johnson Chelsea N, Csikos Vivien, Franczak Edziu, Benson Maggie, Gilmore Caleb A, Birky Cole J, Davis Xin, McCoin Colin S, Smith Keith P, Puchalska Patrycja, Crawford Peter, Slawson Chad, Thyfault John P, Geiger Paige C, Morris Jill K, Wilkins Heather M

A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity

巨噬细胞迁移抑制因子 2 (MIF-2) 的选择性小分子抑制剂,MIF 细胞因子超家族成员,可抑制 MIF-2 的生物活性

Pathricia Veronica Tilstam, Georgios Pantouris, Michael Corman, Monica Andreoli, Keyvan Mahboubi, Gary Davis, Xin Du, Lin Leng, Elias Lolis, Richard Bucala

Bottom-up GGM algorithm for constructing multilayered hierarchical gene regulatory networks that govern biological pathways or processes

自下而上的GGM算法用于构建控制生物通路或过程的多层级基因调控网络。

Kumari, Sapna; Deng, Wenping; Gunasekara, Chathura; Chiang, Vincent; Chen, Huann-Sheng; Ma, Hao; Davis, Xin; Wei, Hairong