日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aging and injury drive neuronal senescence in the dorsal root ganglia.

衰老和损伤会导致背根神经节神经元衰老

Donovan Lauren J, Brewer Chelsie L, Bond Sabrina F, Laslavic Alexander M, Pena Lopez Aleishai, Colman Laura, Jordan Claire E, Hansen Linus H, González Oscar C, Pujari Akshay, de Lecea Luis, Quarta Marco, Kauer Julie A, Tawfik Vivianne L

Cell type specific focused ultrasound neuromodulation in preclinical models of sleep and psychiatric disorders

细胞类型特异性聚焦超声神经调控在睡眠和精神疾病临床前模型中的应用

Murphy, Keith R; de Lecea, Luis

In vivo photocontrol of orexin receptors with a nanomolar light-regulated analogue of orexin-B

利用纳摩尔级光调控的食欲素B类似物对食欲素受体进行体内光控。

Prischich, Davia; Sortino, Rosalba; Gomila-Juaneda, Alexandre; Matera, Carlo; Guardiola, Salvador; Nepomuceno, Diane; Varese, Monica; Bonaventure, Pascal; de Lecea, Luis; Giralt, Ernest; Gorostiza, Pau

Hypocretin-1 receptor antagonism improves inhibitory control during the Go/No-Go task in highly motivated, impulsive male mice

下丘脑泌素-1受体拮抗剂可改善高动机、冲动型雄性小鼠在Go/No-Go任务中的抑制控制能力。

Metha, Jeremy; Ji, Yijun; Braun, Clemens; Nicholson, Janet R; De Lecea, Luis; Murawski, Carsten; Hoyer, Daniel; Jacobson, Laura H

Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning

髓系细胞中固有时钟蛋白BMAL1的缺乏会通过破坏小胶质细胞突触修剪来加速认知衰老。

Iweka, Chinyere Agbaegbu; Seigneur, Erica; Hernandez, Amira Latif; Paredes, Sur Herrera; Cabrera, Mica; Blacher, Eran; Pasternak, Connie Tsai; Longo, Frank M; de Lecea, Luis; Andreasson, Katrin I

High-throughput ultrasound neuromodulation in awake and freely behaving rats

在清醒自由活动的大鼠中进行高通量超声神经调控

Di Ianni, Tommaso; Morrison, Kyle P; Yu, Brenda; Murphy, Keith R; de Lecea, Luis; Airan, Raag D

Lateral hypothalamus hypocretin/orexin glucose-inhibited neurons promote food seeking after calorie restriction.

下丘脑外侧区食欲素/下丘脑泌素葡萄糖抑制神经元在热量限制后促进觅食行为

Teegala Suraj B, Sarkar Pallabi, Siegel Dashiel M, Sheng Zhenyu, Hao Lihong, Bello Nicholas T, De Lecea Luis, Beck Kevin D, Routh Vanessa H

Automated Sleep Deprivation Setup Using a Shaking Platform in Mice

利用摇晃平台在小鼠中建立自动化睡眠剥夺模型

Bian, Wen-Jie; De Lecea, Luis

A tool for monitoring cell type-specific focused ultrasound neuromodulation and control of chronic epilepsy

用于监测细胞类型特异性聚焦超声神经调控和控制慢性癫痫的工具

Murphy, Keith R; Farrell, Jordan S; Gomez, Juan L; Stedman, Quintin G; Li, Ningrui; Leung, Steven A; Good, Cameron H; Qiu, Zhihai; Firouzi, Kamyar; Butts Pauly, Kim; Khuri-Yakub, Butrus Pierre T; Michaelides, Michael; Soltesz, Ivan; de Lecea, Luis

The brake matters: Hyperexcitable arousal circuits in sleep fragmentation with age

刹车机制至关重要:睡眠碎片化与年龄增长相关的过度兴奋的觉醒回路

Li, Shi-Bin; de Lecea, Luis