日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Synthesis and Pharmacological Evaluation of 6,7-Dihydro‑3H‑Oxazolo[3,4‑a]Pyrazine-5,8-Dione Compounds as Inhibitors of Phosphodiesterases 4 and 5

6,7-二氢-3H-噁唑并[3,4-a]吡嗪-5,8-二酮类化合物作为磷酸二酯酶4和5抑制剂的合成及药理学评价

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5c00525
Helfstein, Débora Rocha; das Virgens, Marcio Fernando; Rojas Moscoso, Julio Alejandro; Zaminelli, Tiago; Toledo, Fabiano Travanca; Maia de Lima, Jeniffer; Medeiros, Larissa Ozols; Marcello, Bianca Alves; Soares, Vinícius Marques; Passos, Gabriela Reolon; de Padua, Sarah Saraiva; Wolf, Matheus Eduardo Gonçalves; Carneiro, Leonardo Martins; De Nucci, Gilberto; Keppler, Artur Franz; Mónica, Fabíola Zakia
发表日期：2026
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6-Nitrodopamine Potentiates Catecholamine-Induced Ca(2+) (i) Release in Human Aortic Smooth Muscle and Modulates Vascular Smooth Muscle Contractility

6-硝基多巴胺增强儿茶酚胺诱导的人主动脉平滑肌中Ca(2+) (i)释放并调节血管平滑肌收缩性

期刊:Basic & Clinical Pharmacology & Toxicology
影响因子:3.3
doi:10.1111/bcpt.70224
Britto-Júnior, José; Lima, Antonio Tiago; Qiao, Shuaihua; Tang, Hou Fong; Cardenas, Valerie; Antunes, Edson; De Nucci, Gilberto; Ferro, Albert
Human
发表日期：2026
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Cardiovascular effects of 6-nitrodopamine, adrenaline, noradrenaline, and dopamine in normotensive and hypertensive rats

6-硝基多巴胺、肾上腺素、去甲肾上腺素和多巴胺对正常血压和高血压大鼠心血管的影响

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1557997
Fuguhara, Vivian; De Oliveira, Mariana Gonçalves; Aguiar da Silva, Carlos Alberto; Guazzelli, Pedro Renato; Peterson, Larryn W; De Nucci, Gilberto
Rat
心血管
高血压
免疫/内分泌
发表日期：2025
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The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism

腺苷酸环化酶调节剂作为人诱导多能干细胞（hiPSC）来源的心肌细胞中6-硝基多巴胺潜在受体的鉴定及其在心脏正性肌力作用中的相关性

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1597035
Cipollone, Irene; Monaco, Vittoria; Britto-Júnior, José; Lima, Antonio Tiago; Antunes, Edson; Pupo, Andre Sampaio; Iacobucci, Ilaria; Cozzolino, Flora; Monti, Maria; Parisi, Silvia; Divisato, Giuseppina; Cascone, Emanuela; De Simone, Alfonso; Corvino, Angela; Fiorino, Ferdinando; Frecentese, Francesco; Santagada, Vincenzo; Severino, Beatrice; Sparaco, Rosa; Cinque, Pierfrancesco; Vertuccio, Stefania; Caliendo, Giuseppe; De Nucci, Gilberto
信号转导
细胞生物学
发育与干细胞
干细胞
发表日期：2025
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Improved Synthesis of 5-Nitrohomovanillic Acid and 6-Nitrohomovanillic Acid as Probes for Metabolism Studies of Endothelium-Derived Dopamines: Identification in Human Amniotic Fluid

改进的5-硝基高香草酸和6-硝基高香草酸的合成方法作为内皮源性多巴胺代谢研究的探针：在人羊水中的鉴定

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30204096
Sparaco, Rosa; Cinque, Pierfrancesco; Scognamiglio, Antonia; Vertuccio, Stefania; Caliendo, Giuseppe; Fiorino, Ferdinando; Corvino, Angela; Magli, Elisa; Perissutti, Elisa; Santagada, Vincenzo; Severino, Beatrice; Andreozzi, Giorgia; Luciano, Paolo; Dell'Aversano, Carmela; Miller, Alex Henrique; De Nucci, Gilberto; Frecentese, Francesco
Human
代谢
发表日期：2025
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6-Nitrodopamine Release From Mouse Seminal Vesicles Is Dependent on Endothelial Nitric Oxide Synthase (eNOS) Activation.

小鼠精囊中 6-硝基多巴胺的释放依赖于内皮型一氧化氮合酶 (eNOS) 的激活

期刊:Pharmacology Research & Perspectives
影响因子:2.3
doi:10.1002/prp2.70167
Britto-Júnior José, Godoy Pérola Rafaella Cedano, Lima Denis Oliveira, de Souza Valéria B, Schenka André A, Mariano Fernanda V, Jacintho Felipe Fernandes, Hermawan Idam, Shimokawa Hiroaki, Tsutsui Masato, Chiavegatto Silvana, Antunes Edson, De Nucci Gilberto
免疫/内分泌
Mouse
发表日期：2025
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6-Nitrodopamine potentiates catecholamine-induced contractions of human isolated vas deferens

6-硝基多巴胺可增强儿茶酚胺诱导的人类离体输精管收缩

期刊:FASEB BioAdvances
影响因子:2
doi:10.1096/fba.2024-00183
Lima, Antonio Tiago; Jabbour, Sami; Britto-Júnior, José; de Carvalho, Demétrio Martinho Ramos; Fregonesi, Adriano; Mariano, Fernanda V; de Souza, Valéria Barbosa; Schenka, Andre Almeida; Antunes, Edson; De Nucci, Gilberto
发表日期：2025
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Pharmacological and immunohistochemical characterization of dopamine D4 receptor in human umbilical artery and vein

人脐动脉和脐静脉中多巴胺D4受体的药理学和免疫组织化学特征分析

期刊:Vascular Biology
影响因子:
doi:10.1530/VB-24-0010
Guazzelli, Pedro Renato; Britto-Júnior, José; Cedano Godoy P Souza, Pérola Rafaella; Cardoso, Vinicius Francisco; Lima, Antonio Tiago; Mathias Netto, Felipe Caliani; Barbosa de Souza, Valéria; Antunes, Edson; Schenka, André; De Nucci, Gilberto
信号转导
IHC
免疫/内分泌
发表日期：2025
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GKT137831 and hydrogen peroxide increase the release of 6-nitrodopamine from the human umbilical artery, rat-isolated right atrium, and rat-isolated vas deferens

GKT137831 和过氧化氢可增加人脐动脉、大鼠离体右心房和大鼠离体输精管中 6-硝基多巴胺的释放。

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2024.1348876
Britto-Júnior, José; Furlaneto, Rafael; Lima, Antonio Tiago; de Oliveira, Mariana Gonçalves; Severino, Beatrice; Frecentese, Francesco; Fiorino, Ferdinando; Caliendo, Giuseppe; Muscará, Marcelo Nicolás; De Nucci, Gilberto
Rat
发表日期：2024
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Endothelium-derived 6-nitrodopamine is the major mechanism by which nitric oxide relaxes the rabbit isolated aorta

内皮细胞衍生的6-硝基多巴胺是氧化氮舒张兔离体主动脉的主要机制。

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2024.1507802
Santos, Eric Xavier Dos; Britto-Júnior, José; Ribeiro, João Victor; Junior, Gilberto Quirino; Lima, Antonio Tiago; Moraes, Manoel Odorico; Moraes, Maria Elisabete A; Antunes, Edson; Schenka, André; De Nucci, Gilberto
细胞生物学
内皮细胞
发表日期：2024
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