日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model

在小鼠偏头痛模型中,硬脑膜中PAR2的激活可引起急性行为反应和对硝酸甘油的启动作用。

Mason, Bianca N; Hassler, Shayne N; DeFea, Kathryn; Boitano, Scott; Vagner, Josef; Price, Theodore J; Dussor, Greg

β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation

β-Arrestin 偏向蛋白酶激活受体 2 拮抗剂 C781 可限制过敏原诱发的气道高反应性和炎症

Hillary V Schiff, Candy M Rivas, William P Pederson, Estevan Sandoval, Samuel Gillman, Joy Prisco, Moeno Kume, Gregory Dussor, Josef Vagner, Julie G Ledford, Theodore J Price, Kathryn A DeFea, Scott Boitano

Editorial: Opioids in the time of the COVID-19 pandemic: from cellular mechanisms to public health policy

社论:新冠疫情时期的阿片类药物:从细胞机制到公共卫生政策

John, Scott; Walwyn, David R; DeFea, Kathryn; Hales, Tim G; Walwyn, Wendy

C781, a β-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice

C781 是一种针对蛋白酶激活受体 2 (PAR2) 的 β-Arrestin 拮抗剂,在小鼠体内显示出对抗蛋白酶诱发疼痛的功效

Moeno Kume, Ayesha Ahmad, Stephanie Shiers, Michael D Burton, Kathryn A DeFea, Josef Vagner, Gregory Dussor, Scott Boitano, Theodore J Price

Protease-Activated Receptor 2 (PAR2) Expressed in Sensory Neurons Contributes to Signs of Pain and Neuropathy in Paclitaxel Treated Mice.

感觉神经元中表达的蛋白酶激活受体 2 (PAR2) 会导致紫杉醇治疗的小鼠出现疼痛和神经病变症状

Kume Moeno, Ahmad Ayesha, DeFea Kathryn A, Vagner Josef, Dussor Gregory, Boitano Scott, Price Theodore J

Proteinase-activated receptor-2 antagonist C391 inhibits Alternaria-induced airway epithelial signalling and asthma indicators in acute exposure mouse models

蛋白酶激活受体 2 拮抗剂 C391 抑制急性暴露小鼠模型中链格孢菌诱发的气道上皮信号和哮喘指标

Candy M Rivas, Michael C Yee, Kenneth J Addison, Marissa Lovett, Kasturi Pal, Julie G Ledford, Gregory Dussor, Theodore J Price, Josef Vagner, Kathryn A DeFea, Scott Boitano

Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression

链格孢菌通过蛋白酶激活受体-2 表达诱导呼吸道上皮信号传导和炎症反应

Candy M Rivas, Hillary V Schiff, Aubin Moutal, Rajesh Khanna, Pawel R Kiela, Gregory Dussor, Theodore J Price, Josef Vagner, Kathryn A DeFea, Scott Boitano

In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development

NKTR-181(一种部分μ阿片受体激动剂)的体内和体外特性研究,为未来的治疗开发提供了支持。

Lee, Alex S; Tiwari, Suchi; Bishop, Isabel; Matossian, Vartan; Romaneschi, Nicole; Miyazaki, Takahiro; VanderVeen, Laurie; Zalevsky, Jonathan; DeFea, Kathryn; Cahill, Catherine M; Walwyn, Wendy M

Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation

蛋白酶激活受体-2 信号通过 β-arrestin-2 介导链格孢碱性丝氨酸蛋白酶诱导的呼吸道炎症

Michael C Yee, Heddie L Nichols, Danny Polley, Mahmoud Saifeddine, Kasturi Pal, Kyu Lee, Emma H Wilson, Michael O Daines, Morley D Hollenberg, Scott Boitano, Kathryn A DeFea

Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium

Smoothened 决定 β-arrestin 介导的 G 蛋白偶联受体 Gpr161 从初级纤毛中去除

Kasturi Pal, Sun-Hee Hwang, Bandarigoda Somatilaka, Hemant Badgandi, Peter K Jackson, Kathryn DeFea, Saikat Mukhopadhyay