日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In silico discovery and mechanistic profiling of STING agonists engaging the transmembrane domain

利用计算机模拟发现和机制分析与跨膜结构域结合的STING激动剂

Junaid, Ahmad; Pandey, Uddav; Ward, Janine; Meghani, Nilesh; Miller, Shannon; Negron, Austin; Ryter, Kendal; Burkhart, David; Mizuno, Nobuyu; DeFilippis, Victor R; Rasheed, Omer

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss In Rhesus Macaques

一种寨卡病毒样颗粒疫苗可减轻恒河猴早期妊娠流产

Jaeger, Hannah K; Smith, Jessica L; Labriola, Caralyn S; Pung, Lydia J; Hagen, Olivia L; Denton, Michael; D'Mello, Rahul J; Parkins, Christopher J; Weber, Whitney C; Medica, Samuel; Kreklywich, Craig N; DeFilippis, Victor R; Bondoc, Stephen; Busman-Sahay, Kathleen; Castro, Jenna N; Zilverberg, Gavin; White, Riely; Terry, Margaret; Barber-Axthelm, Aaron M; Axthelm, Michael K; Smedley, Jeremy; Aliota, Matthew T; Weiler, Andrea M; Friedrich, Thomas C; Estes, Jacob; Morgan, Terry K; Lo, Jamie O; Roberts, Victoria H J; Streblow, Daniel N; Hirsch, Alec J

Characterization of a Novel Transmembrane Activating STING Agonist using Genetically Humanized Mice.

利用基因人源化小鼠对新型跨膜激活STING激动剂进行表征

Mizuno Nobuyo, Abraham Jinu, Jimenez-Perez Kevin, Rose Ian, Springgay Laura, Boehm Dylan, Ando Takeshi, Streblow Daniel, Ward Janine, Miller Shannon, Pandey Uddav, Junaid Ahmad, Joyner David, Muir Roshell, Haddad Elias K, Burkhart David, Rasheed Omer, DeFilippis Victor R

Comparative Molecular, Innate, and Adaptive Impacts of Chemically Diverse STING Agonists.

化学性质各异的 STING 激动剂的分子、先天和适应性影响的比较研究

Mizuno Nobuyo, Boehm Dylan, Jimenez-Perez Kevin, Abraham Jinu, Springgay Laura, Rose Ian, DeFilippis Victor R

Development of a next-generation chikungunya virus vaccine based on the HydroVax platform

基于HydroVax平台开发下一代基孔肯雅病毒疫苗

Slifka, Dawn K; Raué, Hans-Peter; Weber, Whitney C; Andoh, Takeshi F; Kreklywich, Craig N; DeFilippis, Victor R; Streblow, Daniel N; Slifka, Mark K; Amanna, Ian J

Herpes simplex virus type 1 inflammasome activation in proinflammatory human macrophages is dependent on NLRP3, ASC, and caspase-1

单纯疱疹病毒1型炎症小体在促炎性人巨噬细胞中的激活依赖于NLRP3、ASC和caspase-1。

Karaba, Andrew H; Figueroa, Alexis; Massaccesi, Guido; Botto, Sara; DeFilippis, Victor R; Cox, Andrea L

Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist

新型人类干扰素基因刺激因子激动剂的发现和机制研究

Zhang, Xiaohui; Liu, Bowei; Tang, Liudi; Su, Qing; Hwang, Nicky; Sehgal, Mohit; Cheng, Junjun; Ma, Julia; Zhang, Xuexiang; Tan, Yinfei; Zhou, Yan; Duan, Zhongping; DeFilippis, Victor R; Viswanathan, Usha; Kulp, John; Du, Yanming; Guo, Ju-Tao; Chang, Jinhong

Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues

寨卡病毒感染恒河猴会导致病毒在多种组织中持续存在。

Hirsch, Alec J; Smith, Jessica L; Haese, Nicole N; Broeckel, Rebecca M; Parkins, Christopher J; Kreklywich, Craig; DeFilippis, Victor R; Denton, Michael; Smith, Patricia P; Messer, William B; Colgin, Lois M A; Ducore, Rebecca M; Grigsby, Peta L; Hennebold, Jon D; Swanson, Tonya; Legasse, Alfred W; Axthelm, Michael K; MacAllister, Rhonda; Wiley, Clayton A; Nelson, Jay A; Streblow, Daniel N

Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues

更正:寨卡病毒感染恒河猴会导致病毒在多种组织中持续存在。

Hirsch, Alec J; Smith, Jessica L; Haese, Nicole N; Broeckel, Rebecca M; Parkins, Christopher J; Kreklywich, Craig; DeFilippis, Victor R; Denton, Michael; Smith, Patricia P; Messer, William B; Colgin, Lois M A; Ducore, Rebecca M; Grigsby, Peta L; Hennebold, Jon D; Swanson, Tonya; Legasse, Alfred W; Axthelm, Michael K; MacAllister, Rhonda; Wiley, Clayton A; Nelson, Jay A; Streblow, Daniel N

Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus

TGF-β 生成失调是老年人易感染基孔肯雅病毒的根本原因

Uhrlaub, Jennifer L; Pulko, Vesna; DeFilippis, Victor R; Broeckel, Rebecca; Streblow, Daniel N; Coleman, Gary D; Park, Byung S; Lindo, John F; Vickers, Ivan; Anzinger, Joshua J; Nikolich-Žugich, Janko