日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthetic GM1 improves motor and memory dysfunctions in mice with monoallelic or biallelic disruption of GM3 synthase

合成的GM1可改善GM3合成酶单等位基因或双等位基因缺失小鼠的运动和记忆功能障碍

Chowdhury, Suman; Kumar, Ranjeet; Zepeda, Evelyn; DeFrees, Shawn; Ledeen, Robert

Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Class A β-lactamase

保守的Asp-Asp碱基对的突变会损害CTX-M A类β-内酰胺酶的结构、功能和抑制作用。

Kemp, M Trent; Nichols, Derek A; Zhang, Xiujun; Defrees, Kyle; Na, Insung; Renslo, Adam R; Chen, Yu

A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans

用于生产含有类人 O-连接聚糖的治疗性蛋白质的细菌表达平台

Ting Du, Nakita Buenbrazo, Laura Kell, Sadia Rahmani, Lyann Sim, Stephen G Withers, Shawn DeFrees, Warren Wakarchuk

An Empirical Study of Amide-Heteroarene π-Stacking Interactions Using Reversible Inhibitors of a Bacterial Serine Hydrolase

使用细菌丝氨酸水解酶的可逆抑制剂对酰胺-杂芳烃 π 堆积相互作用进行实证研究

Kyle DeFrees, M Trent Kemp, Xochina ElHilali-Pollard, Xiujun Zhang, Ahmed Mohamed, Yu Chen, Adam R Renslo

Antibacterial Spectrum of a Tetrazole-Based Reversible Inhibitor of Serine β-Lactamases

四唑类可逆丝氨酸β-内酰胺酶抑制剂的抗菌谱

Pemberton, Orville A; Zhang, Xiujun; Nichols, Derek A; DeFrees, Kyle; Jaishankar, Priyadarshini; Bonnet, Richard; Adams, Jessie; Shaw, Lindsey N; Renslo, Adam R; Chen, Yu

Effect of pendant group on pDNA delivery by cationic-β-cyclodextrin:alkyl-PVA-PEG pendant polymer complexes

侧链基团对阳离子-β-环糊精:烷基-PVA-PEG侧链聚合物复合物递送pDNA的影响

Kulkarni, Aditya; Badwaik, Vivek; DeFrees, Kyle; Schuldt, Ryan A; Gunasekera, Dinara S; Powers, Cory; Vlahu, Alexander; VerHeul, Ross; Thompson, David H

Microfluidic Assembly of Cationic-β-Cyclodextrin:Hyaluronic Acid-Adamantane Host:Guest pDNA Nanoparticles

阳离子-β-环糊精:透明质酸-金刚烷主体:客体pDNA纳米粒子的微流控组装

Kulkarni, Aditya; Verheul, Ross; Defrees, Kyle; Collins, Christopher J; Schuldt, Ryan A; Vlahu, Alexander; Thompson, David H

Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli

在大肠杆菌中表达活性人唾液酸转移酶ST6GalNAcI

Skretas, Georgios; Carroll, Sean; DeFrees, Shawn; Schwartz, Marc F; Johnson, Karl F; Georgiou, George