日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

高通量筛选可识别与 RAS:SOS:RAS 复合物结合并干扰 RAS 信号的小分子

Michael C Burns, Jennifer E Howes, Qi Sun, Andrew J Little, DeMarco V Camper, Jason R Abbott, Jason Phan, Taekyu Lee, Alex G Waterson, Olivia W Rossanese, Stephen W Fesik

Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors

发现和生物学表征强效髓系细胞白血病-1抑制剂

Taekyu Lee ,Zhiguo Bian ,Bin Zhao ,Leah J Hogdal ,John L Sensintaffar ,Craig M Goodwin ,Johannes Belmar ,Subrata Shaw ,James C Tarr ,Nagarathanam Veerasamy ,Shannon M Matulis ,Brian Koss ,Melissa A Fischer ,Allison L Arnold ,DeMarco V Camper ,Carrie F Browning ,Olivia W Rossanese ,Amit Budhraja ,Joseph Opferman ,Lawrence H Boise ,Michael R Savona ,Anthony Letai ,Edward T Olejniczak ,Stephen W Fesik

Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A

鉴定和优化基于邻氨基苯甲酸的复制蛋白A抑制剂

Patrone, James D; Pelz, Nicholas F; Bates, Brittney S; Souza-Fagundes, Elaine M; Vangamudi, Bhavatarini; Camper, Demarco V; Kuznetsov, Alexey G; Browning, Carrie F; Feldkamp, Michael D; Frank, Andreas O; Gilston, Benjamin A; Olejniczak, Edward T; Rossanese, Olivia W; Waterson, Alex G; Chazin, Walter J; Fesik, Stephen W

Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design

使用基于片段的方法和基于结构的设计发现能有效抑制 Mcl-1 的三环吲哚

Jason P Burke, Zhiguo Bian, Subrata Shaw, Bin Zhao, Craig M Goodwin, Johannes Belmar, Carrie F Browning, Dominico Vigil, Anders Friberg, DeMarco V Camper, Olivia W Rossanese, Taekyu Lee, Edward T Olejniczak, Stephen W Fesik

Erythropoietin acts as a trophic factor in neonatal rat intestine.

红细胞生成素在新生大鼠肠道中起营养因子的作用

Juul S E, Ledbetter D J, Joyce A E, Dame C, Christensen R D, Zhao Y, DeMarco V

Elections and public health

选举与公共卫生

DeMarco, V; Schneider, G E