日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

基于片段和结构的药物发现，用于开发靶向DNA损伤反应的治疗药物

期刊:Progress in Biophysics & Molecular Biology
影响因子:4.5
doi:10.1016/j.pbiomolbio.2020.10.005
Wilson, David M 3rd; Deacon, Ashley M; Duncton, Matthew A J; Pellicena, Patricia; Georgiadis, Millie M; Yeh, Andrew P; Arvai, Andrew S; Moiani, Davide; Tainer, John A; Das, Debanu
毒理研究
发表日期：2021
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Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH)

早期药物发现和针对DNA聚合酶Eta（POLH）的新型癌症治疗药物的开发

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2021.778925
Wilson, David M; Duncton, Matthew A J; Chang, Caleb; Lee Luo, Christie; Georgiadis, Taxiarchis M; Pellicena, Patricia; Deacon, Ashley M; Gao, Yang; Das, Debanu
肿瘤
POLH
肿瘤免疫
发表日期：2021
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Structures of single-layer β-sheet proteins evolved from β-hairpin repeats.

单层β折叠蛋白的结构是由β发夹重复序列演化而来

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.3683
Xu Qingping, Biancalana Matthew, Grant Joanna C, Chiu Hsiu-Ju, Jaroszewski Lukasz, Knuth Mark W, Lesley Scott A, Godzik Adam, Elsliger Marc-André, Deacon Ashley M, Wilson Ian A
免疫/内分泌
发表日期：2019
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UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex

RBM39-U2AF65剪接因子复合物中的UHM-ULM相互作用

期刊:Acta Crystallographica Section D-Structural Biology
影响因子:3.8
doi:10.1107/S2059798316001248
Stepanyuk, Galina A; Serrano, Pedro; Peralta, Eigen; Farr, Carol L; Axelrod, Herbert L; Geralt, Michael; Das, Debanu; Chiu, Hsiu-Ju; Jaroszewski, Lukasz; Deacon, Ashley M; Lesley, Scott A; Elsliger, Marc-André; Godzik, Adam; Wilson, Ian A; Wüthrich, Kurt; Salomon, Daniel R; Williamson, James R
发表日期：2016
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Cofactor-induced reversible folding of Flavodoxin-4 from Lactobacillus acidophilus

嗜酸乳杆菌黄素蛋白-4的辅因子诱导可逆折叠

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.2743
Dutta, Samit Kumar; Serrano, Pedro; Geralt, Michael; Axelrod, Herbert L; Xu, Qingping; Lesley, Scott A; Godzik, Adam; Deacon, Ashley M; Elsliger, Marc-André; Wilson, Ian A; Wüthrich, Kurt
发表日期：2015
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Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

对含有细菌SH3结构域的NlpC/P60细胞壁水解酶底物特异性的深入研究

期刊:mBio
影响因子:4.7
doi:10.1128/mBio.02327-14
Xu, Qingping; Mengin-Lecreulx, Dominique; Liu, Xueqian W; Patin, Delphine; Farr, Carol L; Grant, Joanna C; Chiu, Hsiu-Ju; Jaroszewski, Lukasz; Knuth, Mark W; Godzik, Adam; Lesley, Scott A; Elsliger, Marc-André; Deacon, Ashley M; Wilson, Ian A
微生物学
细胞生物学
发表日期：2015
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Cell fate regulation governed by a repurposed bacterial histidine kinase.

细胞命运调控由一种重新利用的细菌组氨酸激酶控制

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.1001979
Childers W Seth, Xu Qingping, Mann Thomas H, Mathews Irimpan I, Blair Jimmy A, Deacon Ashley M, Shapiro Lucy
细胞生物学
发表日期：2014
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Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake

三种新型Pfam家族PF14869（DUF4488）成员的晶体结构表明，它们在糖结合/吸收中发挥作用。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.2522
Kumar, Abhinav; Punta, Marco; Axelrod, Herbert L; Das, Debanu; Farr, Carol L; Grant, Joanna C; Chiu, Hsiu-Ju; Miller, Mitchell D; Coggill, Penelope C; Klock, Heath E; Elsliger, Marc-André; Deacon, Ashley M; Godzik, Adam; Lesley, Scott A; Wilson, Ian A
发表日期：2014
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Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome

人类微生物组中新型吡哆醛-5'-磷酸依赖性酶的分子表征

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.2493
Fleischman, Nicholas M; Das, Debanu; Kumar, Abhinav; Xu, Qingping; Chiu, Hsiu-Ju; Jaroszewski, Lukasz; Knuth, Mark W; Klock, Heath E; Miller, Mitchell D; Elsliger, Marc-André; Godzik, Adam; Lesley, Scott A; Deacon, Ashley M; Wilson, Ian A; Toney, Michael D
微生物学
发表日期：2014
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Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site

一种新型双加氧酶家族成员（PF10014）的晶体结构揭示了其保守的杯状折叠和活性位点。

期刊:Proteins-Structure Function and Bioinformatics
影响因子:2.8
doi:10.1002/prot.24362
Xu, Qingping; Grant, Joanna; Chiu, Hsiu-Ju; Farr, Carol L; Jaroszewski, Lukasz; Knuth, Mark W; Miller, Mitchell D; Lesley, Scott A; Godzik, Adam; Elsliger, Marc-André; Deacon, Ashley M; Wilson, Ian A
发表日期：2014
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