日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IFN-γ and CD25 drive distinct pathologic features during hemophagocytic lymphohistiocytosis

IFN-γ 和 CD25 在噬血细胞性淋巴组织细胞增生症期间驱动不同的病理特征

Stéphanie Humblet-Baron, Dean Franckaert, James Dooley, Fatima Ailal, Aziz Bousfiha, Caroline Deswarte, Carmen Oleaga-Quintas, Jean-Laurent Casanova, Jacinta Bustamante, Adrian Liston

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

β 细胞脆弱的遗传倾向是 1 型和 2 型糖尿病的根本原因

James Dooley, Lei Tian, Susann Schonefeldt, Viviane Delghingaro-Augusto, Josselyn E Garcia-Perez, Emanuela Pasciuto, Daniele Di Marino, Edward J Carr, Nikolay Oskolkov, Valeriya Lyssenko, Dean Franckaert, Vasiliki Lagou, Lut Overbergh, Jonathan Vandenbussche, Joke Allemeersch, Genevieve Chabot-Roy, 

Premature thymic involution is independent of structural plasticity of the thymic stroma

胸腺过早退化与胸腺基质的结构可塑性无关

Dean Franckaert, Susan M Schlenner, Nathalie Heirman, Jason Gill, Gabriel Skogberg, Olov Ekwall, Karen Put, Michelle A Linterman, James Dooley, Adrian Liston

Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells

混杂的 Foxp3-cre 活性揭示了 Foxp3⁺ 和 Foxp3⁻ T 细胞对 CD28 的不同需求

Dean Franckaert, James Dooley, Evelyne Roos, Stefan Floess, Jochen Huehn, Herve Luche, Hans Joerg Fehling, Adrian Liston, Michelle A Linterman, Susan M Schlenner

A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling

一种新的 Zap70 突变导致蛋白质稳定性降低,证明了 Zap70 在 T 细胞受体信号传导中的限速阈值

Bénédicte Cauwe, Lei Tian, Dean Franckaert, Wim Pierson, Kim A Staats, Susan M Schlenner, Adrian Liston

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells

抗凋亡 Mcl-1 对 Foxp3⁺ 调节性 T 细胞的生存和生态位填充能力至关重要

Wim Pierson, Bénédicte Cauwe, Antonia Policheni, Susan M Schlenner, Dean Franckaert, Julien Berges, Stephanie Humblet-Baron, Susann Schönefeldt, Marco J Herold, David Hildeman, Andreas Strasser, Philippe Bouillet, Li-Fan Lu, Patrick Matthys, Antonio A Freitas, Rita J Luther, Casey T Weaver, James Do

Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis

Foxp3⁺ 调节性 T 细胞通过诱导 Th2 细胞凋亡对小鼠辅助反应施加不对称控制

Lei Tian, John A Altin, Lydia E Makaroff, Dean Franckaert, Matthew C Cook, Christopher C Goodnow, James Dooley, Adrian Liston