S1P-S1PR1 signaling impairs CD8(+) T cell metabolism and effector function in tumors
S1P-S1PR1信号通路会损害肿瘤中CD8(+) T细胞的代谢和效应功能。
期刊:EMBO Reports
影响因子:6.2
doi:10.1038/s44319-026-00734-3
Basak, Debashree; Ghosh, Puspendu; Gautam, Anupam; Sarkar, Ishita; Bhoumik, Arpita; Chowdhury, Soham; Mahanti, Shaun; Mandal, Anwesha; Chakraborty, Rajeswari; Kar, Anwesha; Chowdhury, Snehanshu; Kumar, Krishna; Barman, Shubhrajit; Ganesan, Senthil Kumar; Chakrabarti, Saikat; Paul, Sandip; Chatterjee, Shilpak
信号转导
CD8
代谢
免疫/内分泌
细胞生物学
T细胞
S1PR1
肿瘤
肿瘤免疫
T细胞
