Successful Therapy of Murine Visceral Leishmaniasis with Astrakurkurone, a Triterpene Isolated from the Mushroom Astraeus hygrometricus, Involves the Induction of Protective Cell-Mediated Immunity and TLR9
利用从水生星菇(Astraeus hygrometricus)中分离得到的三萜类化合物星菇酮成功治疗小鼠内脏利什曼病,其机制涉及诱导保护性细胞介导免疫和TLR9。
期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01943-15
Mallick, Suvadip; Dutta, Aritri; Chaudhuri, Ankur; Mukherjee, Debasri; Dey, Somaditya; Halder, Subhadra; Ghosh, Joydip; Mukherjee, Debarati; Sultana, Sirin Salma; Biswas, Gunjan; Lai, Tapan Kumar; Patra, Pradyumna; Sarkar, Indranil; Chakraborty, Sibani; Saha, Bhaskar; Acharya, Krishnendu; Pal, Chiranjib