Debatis相关文献与解析，生知库 | 链接生命科学的每一步

Debatis, Michelle; Danz, Hillary; Tremblay, Jacqueline M; Gaspie, Kimberly; Kudej, Raymond K; Vigdorovich, Vladimir; Sather, Noah; Jaskiewicz, Justyna J; Tzipori, Saul; Shoemaker, Charles B

发表日期：2023

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Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes

肌肉内注射编码六个连接纳米抗体的配制 RNA 可高度保护人体免受三种肉毒杆菌毒素血清型的侵害

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-022-15876-2

Jean Mukherjee, Celinia A Ondeck, Jacqueline M Tremblay, Jacob Archer, Michelle Debatis, Alexa Foss, Junya Awata, Jesse H Erasmus, Patrick M McNutt, Charles B Shoemaker

免疫

发表日期：2022

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Human small intestinal organotypic culture model for drug permeation, inflammation, and toxicity assays

用于药物渗透、炎症和毒性试验的人类小肠类器官培养模型

期刊:in Vitro Cellular & Developmental Biology-Animal

影响因子:1.7

doi:10.1007/s11626-020-00526-6

Markus, Jan; Landry, Tim; Stevens, Zachary; Scott, Hailey; Llanos, Pierre; Debatis, Michelle; Armento, Alexander; Klausner, Mitchell; Ayehunie, Seyoum

Human

发表日期：2021

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Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Proteins

曼氏血吸虫感染小鼠、大鼠和人类后，可对五种主要被膜蛋白上数量有限的还原敏感表位产生强烈的抗体反应。

期刊:PLoS Neglected Tropical Diseases

影响因子:3.4

doi:10.1371/journal.pntd.0005306

Krautz-Peterson, Greice; Debatis, Michelle; Tremblay, Jacqueline M; Oliveira, Sergio C; Da'dara, Akram A; Skelly, Patrick J; Shoemaker, Charles B

A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection

一种基于四特异性VHH的中和抗体可改变三种艰难梭菌感染动物模型的疾病结局

期刊:Clinical and Vaccine Immunology

影响因子:

doi:10.1128/CVI.00730-15

Schmidt, Diane J; Beamer, Gillian; Tremblay, Jacqueline M; Steele, Jennifer A; Kim, Hyeun Bum; Wang, Yaunkai; Debatis, Michele; Sun, Xingmin; Kashentseva, Elena A; Dmitriev, Igor P; Curiel, David T; Shoemaker, Charles B; Tzipori, Saul

炎症/感染

发表日期：2016

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Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

利用腺病毒表达靶向保护性抗原的双特异性VHH基中和剂，可为小鼠提供炭疽病的预防性保护

期刊:Clinical and Vaccine Immunology

影响因子:

doi:10.1128/CVI.00611-15

Moayeri, Mahtab; Tremblay, Jacqueline M; Debatis, Michelle; Dmitriev, Igor P; Kashentseva, Elena A; Yeh, Anthony J; Cheung, Gordon Y C; Curiel, David T; Leppla, Stephen; Shoemaker, Charles B

Algal chloroplast produced camelid VH H antitoxins are capable of neutralizing botulinum neurotoxin

藻类叶绿体产生的骆驼科动物VH H抗毒素能够中和肉毒杆菌神经毒素

期刊:Plant Biotechnology Journal

影响因子:10.5

doi:10.1111/pbi.12244

Barrera, Daniel J; Rosenberg, Julian N; Chiu, Joanna G; Chang, Yung-Nien; Debatis, Michelle; Ngoi, Soo-Mun; Chang, John T; Shoemaker, Charles B; Oyler, George A; Mayfield, Stephen P

发表日期：2015

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Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication

表达 Stx1/Stx2 中和剂的腺病毒载体可保护感染大肠杆菌 O157:H7 的仔猪免受致命性全身中毒。

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.02360-14

Sheoran, Abhineet S; Dmitriev, Igor P; Kashentseva, Elena A; Cohen, Ocean; Mukherjee, Jean; Debatis, Michelle; Shearer, Jonathan; Tremblay, Jacqueline M; Beamer, Gillian; Curiel, David T; Shoemaker, Charles B; Tzipori, Saul

The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells

布鲁顿酪氨酸激酶在 AM14 类风湿因子 B 细胞发育和 BCR/TLR 依赖性激活中的作用

期刊:Journal of Leukocyte Biology

影响因子:3.6

doi:10.1189/jlb.0313126

Kerstin Nündel, Patricia Busto, Michelle Debatis, Ann Marshak-Rothstein

A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2

一种基于VHH的毒素中和剂和一种效应抗体可以保护小鼠免受志贺毒素1和2的攻击。

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.01033-13

Tremblay, Jacqueline M; Mukherjee, Jean; Leysath, Clinton E; Debatis, Michelle; Ofori, Kwasi; Baldwin, Karen; Boucher, Courtney; Peters, Rachel; Beamer, Gillian; Sheoran, Abhineet; Bedenice, Daniela; Tzipori, Saul; Shoemaker, Charles B

发表日期：2013

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Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies

骆驼科单体和多聚体纳米抗体单域抗体的肠道药代动力学

Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes

肌肉内注射编码六个连接纳米抗体的配制 RNA 可高度保护人体免受三种肉毒杆菌毒素血清型的侵害

Human small intestinal organotypic culture model for drug permeation, inflammation, and toxicity assays

用于药物渗透、炎症和毒性试验的人类小肠类器官培养模型

Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Proteins

曼氏血吸虫感染小鼠、大鼠和人类后，可对五种主要被膜蛋白上数量有限的还原敏感表位产生强烈的抗体反应。

A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection

一种基于四特异性VHH的中和抗体可改变三种艰难梭菌感染动物模型的疾病结局

Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

利用腺病毒表达靶向保护性抗原的双特异性VHH基中和剂，可为小鼠提供炭疽病的预防性保护

Algal chloroplast produced camelid VH H antitoxins are capable of neutralizing botulinum neurotoxin

藻类叶绿体产生的骆驼科动物VH H抗毒素能够中和肉毒杆菌神经毒素

Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication

表达 Stx1/Stx2 中和剂的腺病毒载体可保护感染大肠杆菌 O157:H7 的仔猪免受致命性全身中毒。

The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells

布鲁顿酪氨酸激酶在 AM14 类风湿因子 B 细胞发育和 BCR/TLR 依赖性激活中的作用

A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2

一种基于VHH的毒素中和剂和一种效应抗体可以保护小鼠免受志贺毒素1和2的攻击。