Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss
Wnt1 依赖性小鼠乳腺癌模型中的肿瘤逃逸是由 p19Arf/p53 通路损伤而非 p16 Ink4a 缺失引起的
期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI33320
Michael T Debies, Shelley A Gestl, Jessica L Mathers, Oliver R Mikse, Travis L Leonard, Susan E Moody, Lewis A Chodosh, Robert D Cardiff, Edward J Gunther
信号转导
肿瘤
乳腺癌
Wnt/β-Catenin
Mouse