日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Reduction

PROTAC 介导的胞质可溶性环氧化物水解酶选择性降解增强内质网应激减轻

Yuxin Wang, Christophe Morisseau, Akihiro Takamura, Debin Wan, Dongyang Li, Simone Sidoli, Jun Yang, Dennis W Wolan, Bruce D Hammock, Seiya Kitamura

Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor

利用可溶性环氧化物水解酶抑制剂,在小鼠哮喘模型中开发出一种治疗气道高反应性和炎症的新型气溶胶疗法。

Chuanzhen Zhang ,Wei Li ,Xiyuan Li ,Debin Wan ,Savannah Mack ,Jingjing Zhang ,Karen Wagner ,Chang Wang ,Bowen Tan ,Jason Chen ,Ching-Wen Wu ,Kaori Tsuji ,Minoru Takeuchi ,Ziping Chen ,Bruce D Hammock ,Kent E Pinkerton ,Jun Yang

sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury

sEH 衍生的亚油酸代谢物会引发病理性炎症,同时损害烧伤中关键的先天免疫细胞功能

Christian B Bergmann, Cindy B McReynolds, Debin Wan, Nalin Singh, Holly Goetzman, Charles C Caldwell, Dorothy M Supp, Bruce D Hammock

TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function

TPPU 治疗烧伤小鼠可抑制炎症和生物活性 DHET 的产生,从而削弱中性粒细胞功能

Christian B Bergmann, Bruce D Hammock, Debin Wan, Falk Gogolla, Holly Goetzman, Charles C Caldwell, Dorothy M Supp

Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain

肾上腺酸衍生的环氧脂肪酸是天然存在的脂质,其甲酯前药可减轻内质网应激和炎症疼痛

Nalin Singh, Bogdan Barnych, Karen M Wagner, Debin Wan, Christophe Morisseau, Bruce D Hammock

Development of nanobody-based flow-through dot ELISA and lateral-flow immunoassay for rapid detection of 3-phenoxybenzoic acid

基于纳米抗体的流通点 ELISA 和侧流免疫分析法快速检测 3-苯氧基苯甲酸的开发

Can Zhang, Xiaoxiao Wu, Dongyang Li, Jinnuo Hu, Debin Wan, Zhen Zhang, Bruce D Hammock

A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis

可溶性环氧化物水解酶抑制剂 1-三氟甲氧基苯基-3-(1-丙酰哌啶-4-基)脲可改善实验性自身免疫性脑脊髓炎

Deepa Jonnalagadda, Debin Wan, Jerold Chun, Bruce D Hammock, Yasuyuki Kihara

An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease

环氧化物水解酶抑制剂可减轻阿尔茨海默病小鼠模型中的神经炎症

Anamitra Ghosh, Michele M Comerota, Debin Wan, Fading Chen, Nicholas E Propson, Sung Hee Hwang, Bruce D Hammock, Hui Zheng

Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

维生素 D 缺乏是斑马鱼生长迟缓和中心性肥胖的前兆

Megan M Knuth, Debabrata Mahapatra, Dereje Jima, Debin Wan, Bruce D Hammock, Mac Law, Seth W Kullman

Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity

t-TUCB 抑制可溶性环氧化物水解酶可促进棕色脂肪生成并降低饮食引起的肥胖中的血清甘油三酯

Haley Overby, Yang Yang, Xinyun Xu, Katherine Graham, Kelsey Hildreth, Sue Choi, Debin Wan, Christophe Morisseau, Darryl C Zeldin, Bruce D Hammock, Shu Wang, Ahmed Bettaieb, Ling Zhao