Debley Jason S相关文献与解析，生知库 | 链接生命科学的每一步

Bronchial epithelial transcriptome reveals dysregulated interferon and inflammatory responses to rhinovirus in exacerbation-prone pediatric asthma

支气管上皮转录组揭示易急性发作儿童哮喘中鼻病毒引起的干扰素和炎症反应失调

doi:10.1172/jci.insight.197711

Doni Jayavelu, Naresh; Benson, Basilin; Dela Cruz, Patricia C; Powell, Weston T; Rich, Lucille M; Vanderwall, Elizabeth R; Gates, Camile R; Nagel, Andrew J; White, Maria P; Samanas, Nyssa B; Whitfield, Kourtnie; Hallstrand, Teal S; Ziegler, Steven F; Altman, Matthew C; Debley, Jason S

Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma

支气管上皮转录组分析揭示易急性发作型儿童哮喘中鼻病毒引起的干扰素和炎症反应失调

期刊:

影响因子:

doi:10.1101/2025.10.19.683298

Jayavelu, Naresh Doni; Benson, Basilin; Dela Cruz, Patricia C; Powell, Weston T; Rich, Lucille M; Vanderwall, Elizabeth R; Gates, Camile R; Nagel, Andrew J; White, Maria P; Samanas, Nyssa B; Whitfield, Kourtnie; Hallstrand, Teal S; Ziegler, Steven F; Altman, Matthew C; Debley, Jason S

IL-13 Modulates Antiviral Effector and Proinflammatory Pathways in Rhinovirus-Infected Pediatric Bronchial Epithelium

IL-13 调节鼻病毒感染的儿童支气管上皮细胞中的抗病毒效应通路和促炎通路

期刊:

影响因子:

doi:10.64898/2025.12.06.692776

Dela Cruz, Patricia C; Benson, Basilin; Jayavelu, Naresh Doni; Powell, Weston T; Rich, Lucille M; Vanderwall, Elizabeth R; Gates, Camile R; White, Maria P; Samanas, Nyssa B; Whitfield, Kourtnie; Hallstrand, Teal S; Ziegler, Steven F; Deutsch, Gail H; Altman, Matthew C; Debley, Jason S

Infants who develop BPD have an airway endotype defined by vimentin expression and ciliary loss

患有支气管肺发育不良（BPD）的婴儿具有一种气道内型，其特征是波形蛋白表达和纤毛丢失。

期刊:

影响因子:

doi:10.1101/2025.09.16.676660

Eldredge, Laurie C; Han, Yan; Deutsch, Gail H; Sucre, Jennifer M S; Shirazi, Shawyon P; Stefani, Caroline; Pribitzer, Stephan; Reeves, Stephen R; Rich, Lucille M; Vanderwall, Elizabeth R; Ziegler, Steven F; Debley, Jason S

发育与干细胞

发表日期：2025

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Viral replication and interferon responses in bronchial epithelia is enhanced by Th17 cells

Th17细胞可增强支气管上皮细胞中的病毒复制和干扰素反应。

期刊:

影响因子:

doi:10.1101/2025.10.10.681711

Powell, Weston T; Janczyk, Tomasz J; Dela Cruz, Patricia C; Benson, Basilin; Vanderwall, Elizabeth R; Gates, Camille R; Rich, Lucille M; White, Maria P; Samanas, Nyssa B; Whitfield, Kourtnie; Deutsch, Gail H; Hallstrand, Teal S; Altman, Matthew C; Debley, Jason S

Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons

鼻病毒感染气道上皮细胞可通过上皮细胞来源的干扰素增强肥大细胞的免疫反应。

期刊:Journal of Allergy and Clinical Immunology

影响因子:11.2

doi:10.1016/j.jaci.2022.12.825

Murphy, Ryan C; Lai, Ying; Altman, Matthew C; Barrow, Kaitlyn A; Dill-McFarland, Kimberly A; Liu, Matthew; Hamerman, Jessica A; Lacy-Hulbert, Adam; Piliponsky, Adrian M; Ziegler, Steven F; Altemeier, William A; Debley, Jason S; Gharib, Sina A; Hallstrand, Teal S

Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma

痰液骨膜蛋白是哮喘中2型炎症的生物标志物，但并非气道功能障碍的生物标志物。

期刊:Respirology

影响因子:6.3

doi:10.1111/resp.14491

Al-Shaikhly, Taha; Murphy, Ryan C; Lai, Ying; Frevert, Charles W; Debley, Jason S; Ziegler, Steven F; Wong, Kit; Jia, Guiquan; Holweg, Cecile T J; Peters, Michael C; Hallstrand, Teal S

Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma

嗜酸性粒细胞在气道壁中的定位对于哮喘气道高反应性和T2炎症的特定特征至关重要。

期刊:European Respiratory Journal

影响因子:21

doi:10.1183/13993003.01865-2021

Al-Shaikhly, Taha; Murphy, Ryan C; Parker, Andrew; Lai, Ying; Altman, Matthew C; Larmore, Megan; Altemeier, William A; Frevert, Charles W; Debley, Jason S; Piliponsky, Adrian M; Ziegler, Steven F; Peters, Michael C; Hallstrand, Teal S

Correction: IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2

更正：源自记忆B细胞的IgM抗体是SARS-CoV-2的有效交叉变异株中和剂。

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.2022084908172022c

Hale, Malika; Netland, Jason; Chen, Yu; Thouvenel, Christopher D; Smith, Katherine Nabel; Rich, Lucille M; Vanderwall, Elizabeth R; Miranda, Marcos C; Eggenberger, Julie; Hao, Linhui; Watson, Michael J; Mundorff, Charles C; Rodda, Lauren B; King, Neil P; Guttman, Miklos; Gale, Michael; Abraham, Jonathan; Debley, Jason S; Pepper, Marion; Rawlings, David J

Optimized primary organotypic culture from murine neonatal tracheal airway epithelial cells

优化小鼠新生儿气管上皮细胞原代类器官培养

Bronchial epithelial transcriptome reveals dysregulated interferon and inflammatory responses to rhinovirus in exacerbation-prone pediatric asthma

支气管上皮转录组揭示易急性发作儿童哮喘中鼻病毒引起的干扰素和炎症反应失调

Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma

支气管上皮转录组分析揭示易急性发作型儿童哮喘中鼻病毒引起的干扰素和炎症反应失调

IL-13 Modulates Antiviral Effector and Proinflammatory Pathways in Rhinovirus-Infected Pediatric Bronchial Epithelium

IL-13 调节鼻病毒感染的儿童支气管上皮细胞中的抗病毒效应通路和促炎通路

Infants who develop BPD have an airway endotype defined by vimentin expression and ciliary loss

患有支气管肺发育不良（BPD）的婴儿具有一种气道内型，其特征是波形蛋白表达和纤毛丢失。

Viral replication and interferon responses in bronchial epithelia is enhanced by Th17 cells

Th17细胞可增强支气管上皮细胞中的病毒复制和干扰素反应。

Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons

鼻病毒感染气道上皮细胞可通过上皮细胞来源的干扰素增强肥大细胞的免疫反应。

Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma

痰液骨膜蛋白是哮喘中2型炎症的生物标志物，但并非气道功能障碍的生物标志物。

Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma

嗜酸性粒细胞在气道壁中的定位对于哮喘气道高反应性和T2炎症的特定特征至关重要。

Correction: IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2

更正：源自记忆B细胞的IgM抗体是SARS-CoV-2的有效交叉变异株中和剂。