Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia
线粒体复合物 I 的种系突变揭示了 IDH1 突变型急性髓系白血病的遗传和可靶向脆弱性
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-30223-9
Mahmoud A Bassal # ,Saumya E Samaraweera # ,Kelly Lim ,Brooks A Benard ,Sheree Bailey ,Satinder Kaur ,Paul Leo ,John Toubia ,Chloe Thompson-Peach ,Tran Nguyen ,Kyaw Ze Ya Maung ,Debora A Casolari ,Diana G Iarossi ,Ilaria S Pagani ,Jason Powell ,Stuart Pitson ,Siria Natera ,Ute Roessner ,Ian D Lewis ,Anna L Brown ,Daniel G Tenen ,Nirmal Robinson ,David M Ross ,Ravindra Majeti ,Thomas J Gonda ,Daniel Thomas ,Richard J D'Andrea