日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity

LRRC15+肌成纤维细胞决定基质的平衡点,从而抑制肿瘤免疫

Akshay T Krishnamurty ,Justin A Shyer ,Minh Thai ,Vineela Gandham ,Matthew B Buechler ,Yeqing Angela Yang ,Rachana N Pradhan ,Amber W Wang ,Patricia L Sanchez ,Yan Qu ,Beatrice Breart ,Cécile Chalouni ,Debra Dunlap ,James Ziai ,Justin Elstrott ,Neelie Zacharias ,Weiguang Mao ,Rebecca K Rowntree ,Jack Sadowsky ,Gail D Lewis ,Thomas H Pillow ,Barzin Y Nabet ,Romain Banchereau ,Lucinda Tam ,Roger Caothien ,Natasha Bacarro ,Merone Roose-Girma ,Zora Modrusan ,Sanjeev Mariathasan ,Sören Müller ,Shannon J Turley

Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers

PROTAC 介导的 SMARCA2 选择性降解对 SMARCA4 突变癌症有效

Jennifer Cantley, Xiaofen Ye, Emma Rousseau, Tom Januario, Brian D Hamman, Christopher M Rose, Tommy K Cheung, Trent Hinkle, Leofal Soto, Connor Quinn, Alicia Harbin, Elizabeth Bortolon, Xin Chen, Roy Haskell, Eva Lin, Shang-Fan Yu, Geoff Del Rosario, Emily Chan, Debra Dunlap, Hartmut Koeppen, Scott

Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer

抗LYPD1/CD3 T细胞依赖性双特异性抗体用于治疗卵巢癌

Amy A Lo, Jennifer Johnston, Ji Li, Danielle Mandikian, Maria Hristopoulos, Robyn Clark, Dorothee Nickles, Wei-Ching Liang, Kathy Hötzel, Debra Dunlap, Thinh Pham, Hao Cai, Meric Ovacik, Daniel Bravo-Perez, Elaine Mai, Dionysos Slaga, Diego Ellerman, James Ziai, Klara Totpal, Genee Lee, C Andrew Bos

The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

肽同向转运体 SLC15a4 对小鼠模型中系统性红斑狼疮的发展至关重要

Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Jason Hackney, Keith Anderson, Tuija M Alcantar, Natasha Bacarro, Debra Dunlap, Jeffrey Eastham, Andres Paler-Martinez, Xin Y Rairdan, Zora Modrusan, Wyne P Lee, Cary D Austin, Daniel Lafkas, Nico Ghilardi

NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma

NRG1是TP63驱动的鳞状细胞癌分化过程中的关键调节因子。

Ganapati V Hegde ,Cecile de la Cruz ,Jennifer M Giltnane ,Lisa Crocker ,Avinashnarayan Venkatanarayan ,Gabriele Schaefer ,Debra Dunlap ,Joerg D Hoeck ,Robert Piskol ,Florian Gnad ,Zora Modrusan ,Frederic J de Sauvage ,Christian W Siebel ,Erica L Jackson