Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants
合成17B-HSD13底物的设计和应用揭示了保护性人类变体的催化活性得以保留
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-54487-5
Garnsey, Michelle R; Wang, Yang; Edmonds, David J; Sammons, Matthew F; Reidich, Benjamin; Ahn, Youngwook; Ashkenazi, Yotam; Carlo, Anthony; Cerny, Matthew A; Coffman, Karen J; Culver, Jeffrey A; Dechert Schmitt, Anne-Marie; Eng, Heather; Fisher, Ethan L; Gutierrez, Jemy A; James, Larry; Jordan, Samantha; Kohrt, Jeffrey T; Kramer, Melissa; LaChapelle, Erik A; Lee, Jack C; Lee, Jisun; Li, Dongmei; Li, Zhenhong; Liu, Shenping; Liu, Jianhua; Magee, Thomas V; Miller, Melissa R; Moran, Michael; Nason, Deane M; Nedoma, Nicole L; O'Neil, Steven V; Piotrowski, Mary A; Racich, Jillian; Sommese, Ruth F; Stevens, Lucy M; Wright, Ann S; Xiao, Jun; Zhang, Liying; Zhou, Dahui; Barrandon, Ornella; Clasquin, Michelle F
