日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Telomere Dysfunction and Proteostasis Decline Define Distinct Pathways of Cellular Senescence in the Human Respiratory Tract

端粒功能障碍和蛋白质稳态下降定义了人类呼吸道细胞衰老的不同途径

Coquette, Céline; Bouchoucha, Kamar; Mahieu, Manon; Verleden, Stijn E; Loriot, Axelle; Norris, Kevin; Baird, Duncan M; Derumier, Amélie; Hoton, Delphine; De Sadeleer, Laurens; Vanstapel, Arno; Vanaudenaerde, Bart M; Goyet, Maëlle de Ville de; Brichard, Bénédicte; Froidure, Antoine; Wuyts, Wim; Van Slambrouck, Jan; Ceulemans, Laurens J; Trigaux, William; Huart, Caroline; Decottignies, Anabelle

Local heterochromatin enrichment promotes telomere clustering and PML nuclear body assembly at telomeres

局部异染色质富集促进端粒聚集和端粒处PML核体组装

Taylor, Erin R; Proctor, Bruce 3rd; Vaurs, Melina; Wu, Guanhui; Mahieu, Manon; Shrestha, Shreya; Morrison, Daniel; Weatherly, Laila; Brelinsky, Shane; Raghunandan, Maya; Decottignies, Anabelle; Arnoult, Nausica

Olfactory decline tracks central-to-peripheral spread of tau pathology in Alzheimer's disease

嗅觉衰退与阿尔茨海默病中tau蛋白病理从中枢向外周的扩散密切相关

Bouchoucha, Kamar; Collin, Lisa; Coquette, Céline; Colmant, Lise; Boyer, Emilien; Huyghe, Lara; Quenon, Lisa; Gerard, Thomas; Salman, Yasmine; Hox, Valérie; Kienlen-Campard, Pascal; Hanseeuw, Bernard; Decottignies, Anabelle; Huart, Caroline

TRF1 relies on fork reversal to prevent fragility at human telomeres

TRF1 依靠复制叉逆转来防止人类端粒的脆弱性。

Vaurs, Mélina; Claude, Eloïse; Zanella, Elia; Rodrigues, Joana; Nassour, Joe; Karlseder, Jan; Azzalin, Claus M; Doksani, Ylli; Decottignies, Anabelle

The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system

嗅觉上皮:病理性tau蛋白传播的关键门户和中枢神经系统tau蛋白病变缓解的靶点

Dourte, Marion; Paître, Esther; Bouchoucha, Mongia; Boyer, Emilien; Tomé, Sandra O; Doeraene, Emilie; Huart, Caroline; Leroy, Karelle; Thal, Dietmar Rudolf; Decottignies, Anabelle; Hanseeuw, Bernard; Suelves, Nuria; Kienlen-Campard, Pascal

Epigenetics of Human Telomeres

人类端粒的表观遗传学

Bettin, Nicole; Vaurs, Mélina; Decottignies, Anabelle

Structural insights into the interaction between testis-specific Y-encoded-like protein 5 and ubiquitin-specific protease 7.

对睾丸特异性 Y 编码样蛋白 5 与泛素特异性蛋白酶 7 相互作用的结构见解

Ancia Marine, Wahni Khadija, Chakrowf Joudy, El Aakchioui Asia, Claude Eloïse, de Lhoneux Guillaume, Liberelle Maxime, Janvier Steven, Baranova Ekaterina, Malo Pueyo Julia, Jijon Vergara Ariana, Papadopoulos Nicolas, Balty Clémence, Dejeu Jérôme, Decottignies Anabelle, Messens Joris, Frédérick Raphaël

Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology

衰老相关的自噬功能障碍会在淀粉样蛋白病理小鼠模型中诱导有毒的神经元内β-淀粉样蛋白积累。

Suelves, Nuria; Saleki, Shirine; Ibrahim, Tasha; Palomares, Debora; Moonen, Sebastiaan; Koper, Marta J; Vrancx, Céline; Vadukul, Devkee M; Papadopoulos, Nicolas; Viceconte, Nikenza; Claude, Eloïse; Vandenberghe, Rik; von Arnim, Christine A F; Constantinescu, Stefan N; Thal, Dietmar Rudolf; Decottignies, Anabelle; Kienlen-Campard, Pascal

Lung Microenvironments and Disease Progression in Fibrotic Hypersensitivity Pneumonitis.

肺微环境与纤维化过敏性肺炎的疾病进展

De Sadeleer Laurens J, McDonough John E, Schupp Jonas C, Yan Xiting, Vanstapel Arno, Van Herck Anke, Everaerts Stephanie, Geudens Vincent, Sacreas Annelore, Goos Tinne, Aelbrecht Celine, Nawrot Tim S, Martens Dries S, Schols Dominique, Claes Sandra, Verschakelen Johny A, Verbeken Eric K, Ackermann Maximilian, Decottignies Anabelle, Mahieu Manon, Hackett Tillie-Louise, Hogg James C, Vanaudenaerde Bart M, Verleden Stijn E, Kaminski Naftali, Wuyts Wim A

Photo-induced telomeric DNA damage in human cancer cells

光诱导人类癌细胞端粒DNA损伤

Weynand, Justin; Episkopou, Harikleia; Le Berre, Gabriel; Gillard, Martin; Dejeu, Jérôme; Decottignies, Anabelle; Defrancq, Eric; Elias, Benjamin