日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats

老年大鼠阿片类药物诱发的术后认知功能障碍的根本原因是海马线粒体功能紊乱。

期刊:
影响因子:
doi:10.64898/2026.01.30.702943
Muscat, Stephanie M; Deems, Nicholas P; Alvarez, Bryan D; Butler, Michael J; Gonzalez Olmo, Brigitte M; Kolonay, Dominic W; Sanders, Hannah F; Scaria, Emmanuel A; Mackey-Alfonso, Sabrina E; Blackwell, Jade A; DeMarsh, James W; Bettes, Menaz N; Quach, Tam T; Cortese, Giuseppe P; Glasper, Erica R; Leuner, Benedetta; Baskin, Kedryn K; Barrientos, Ruth M
线粒体
Rat
神经科学
发表日期：2026
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Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease

通过甘露糖包被的脂质纳米粒子靶向抑制 miR-17 可改善阿尔茨海默病小鼠模型的病理和行为

期刊:Brain Behavior and Immunity
影响因子:8.8
doi:10.1016/j.bbi.2024.05.006
Asmaa Badr, Kylene P Daily, Mostafa Eltobgy, Shady Estfanous, Michelle H Tan, Jimmy Chun-Tien Kuo, Owen Whitham, Cierra Carafice, Gauruv Gupta, Heba M Amer, Mohamed M Shamseldin, Amir Yousif, Nicholas P Deems, Julie Fitzgerald, Pearlly Yan, Amy Webb, Xiaoli Zhang, Maciej Pietrzak, Hazem E Ghoneim, P
阿尔茨海默症
发表日期：2024
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Post-operative cognitive dysfunction is exacerbated by high-fat diet via TLR4 and prevented by dietary DHA supplementation

高脂饮食通过 TLR4 途径加剧术后认知功能障碍，而膳食补充 DHA 则可预防该障碍。

期刊:Brain Behavior and Immunity
影响因子:7.6
doi:10.1016/j.bbi.2023.12.028
Muscat, Stephanie M; Butler, Michael J; Bettes, Menaz N; DeMarsh, James W; Scaria, Emmanuel A; Deems, Nicholas P; Barrientos, Ruth M
TLR4
神经科学
发表日期：2024
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CD8+ T cells contribute to diet-induced memory deficits in aged male rats

CD8+ T细胞在老年雄性大鼠的饮食诱导性记忆缺陷中发挥作用

期刊:Brain Behavior and Immunity
影响因子:8.8
doi:10.1016/j.bbi.2023.02.003
Michael J Butler ，Shouvonik Sengupta ，Stephanie M Muscat ，Stephanie A Amici ，Rebecca G Biltz ，Nicholas P Deems ，Piyush Dravid ，Sabrina Mackey-Alfonso ，Haanya Ijaz ，Menaz N Bettes ，Jonathan P Godbout ，Amit Kapoor ，Mireia Guerau-de-Arellano ，Ruth M Barrientos
免疫/内分泌
Rat
T细胞
细胞生物学
T细胞
CD8
发表日期：2023
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Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats

选择性 TLR4 拮抗剂可预防和逆转老年雄性大鼠吗啡引起的持续性术后认知功能障碍、突触元素失调和 BDNF 信号传导受损

期刊:Journal of Neuroscience
影响因子:4.4
doi:10.1523/JNEUROSCI.1151-22.2022
Stephanie M Muscat, Nicholas P Deems, Michael J Butler, Emmanuel A Scaria, Menaz N Bettes, Sean P Cleary, Ross H Bockbrader, Steven F Maier, Ruth M Barrientos
信号转导
ELISA
IHC-P
WB
发表日期：2023
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Neurodegenerative Diseases: From Dysproteostasis, Altered Calcium Signalosome to Selective Neuronal Vulnerability to AAV-Mediated Gene Therapy

神经退行性疾病：从蛋白质稳态失调、钙信号体改变到神经元对腺相关病毒介导的基因治疗的选择性易感性

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms232214188
Quach, Tam T; Stratton, Harrison J; Khanna, Rajesh; Mackey-Alfonso, Sabrina; Deems, Nicolas; Honnorat, Jérome; Meyer, Kathrin; Duchemin, Anne-Marie
信号转导
基因治疗
神经科学
微生物学
蛋白质稳态
发表日期：2022
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Dietary DHA prevents cognitive impairment and inflammatory gene expression in aged male rats fed a diet enriched with refined carbohydrates

膳食中的DHA可预防以精制碳水化合物为主食的老年雄性大鼠的认知障碍和炎症基因表达。

期刊:Brain Behavior and Immunity
影响因子:7.6
doi:10.1016/j.bbi.2021.08.214
Butler, Michael J; Deems, Nicholas P; Muscat, Stephanie; Butt, Christopher M; Belury, Martha A; Barrientos, Ruth M
炎症/感染
炎症
Rat
神经科学
发表日期：2021
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Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation

阿尔茨海默病患者小胶质细胞中 MiR-17 表达升高可消除自噬介导的淀粉样蛋白-β 降解

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2021.705581
Shady Estfanous, Kylene P Daily, Mostafa Eltobgy, Nicholas P Deems, Midhun N K Anne, Kathrin Krause, Asmaa Badr, Kaitlin Hamilton, Cierra Carafice, Ahmad Hegazi, Arwa Abu Khweek, Hesham Kelani, Shahid Nimjee, Hamdy Awad, Xiaoli Zhang, Estelle Cormet-Boyaka, Hesham Haffez, Sameh Soror, Adel Mikhail, 
信号转导
神经
阿尔茨海默症
胶质细胞
WB
Autophagy
发表日期：2021
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Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats

吗啡治疗可使老年大鼠术后认知功能障碍持续存在。

期刊:Neurobiology of Aging
影响因子:3.5
doi:10.1016/j.neurobiolaging.2020.11.008
Muscat, Stephanie M; Deems, Nicholas P; D'Angelo, Heather; Kitt, Meagan M; Grace, Peter M; Andersen, Nathan D; Silverman, Shaelyn N; Rice, Kenner C; Watkins, Linda R; Maier, Steven F; Barrientos, Ruth M
Rat
神经科学
发表日期：2021
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CD200 promotes immunosuppression in the pancreatic tumor microenvironment

CD200 促进胰腺肿瘤微环境中的免疫抑制

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2019-000189
Fouad Choueiry, Molly Torok, Reena Shakya, Kriti Agrawal, Anna Deems, Brooke Benner, Alice Hinton, Jami Shaffer, Bradley W Blaser, Anne M Noonan, Terence M Williams, Mary Dillhoff, Darwin L Conwell, Phil A Hart, Zobeida Cruz-Monserrate, Xue-Feng Bai, William E Carson 3rd, Thomas A Mace
免疫
肿瘤
发表日期：2020
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