日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Linezolid-mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition.

利奈唑胺通过抑制线粒体翻译来预防成纤维细胞活化和组织纤维化。

期刊:Arthritis & Rheumatology
影响因子:10.9
doi:10.1002/art.43440
Hong Xuezhi, Xiao Yanhua, Qi Haodong, Zhu Shihao, Filla Tim, Györfi Andrea-Hermina, Li Yi-Nan, Xu Meilin, Zhi Langxian, Trinh-Minh Thuong, Dees Clara, Schett Georg, Distler Jörg H W, Matei Alexandru-Emil
细胞生物学
成纤维细胞
线粒体
发表日期：2026
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Mutual Amplification of GLI2/Hedgehog and Transcription Factor JUN/AP-1 Signaling in Fibroblasts in Systemic Sclerosis: Potential Implications for Combined Therapies

系统性硬化症成纤维细胞中GLI2/Hedgehog和转录因子JUN/AP-1信号通路的相互增强：对联合治疗的潜在意义

期刊:Arthritis & Rheumatology
影响因子:10.9
doi:10.1002/art.42979
Bergmann, Christina; Chenguiti Fakhouri, Sara; Trinh-Minh, Thuong; Filla, Tim; Rius Rigau, Aleix; Ekici, Arif B; Merlevede, Benita; Hallenberger, Ludwig; Zhu, Honglin; Dees, Clara; Matei, Alexandru-Emil; Auth, Janina; Györfi, Andrea-Hermina; Zhou, Xiang; Rauber, Simon; Bozec, Aline; Dickel, Nicholas; Liang, Chunguang; Kunz, Meik; Schett, Georg; Distler, Jörg H W
成纤维细胞
信号转导
Hedgehog
系统性硬化症
JUN
细胞生物学
免疫/内分泌
发表日期：2025
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Disturbed Spatial WNT Activation-A Potential Driver of the Reticularized Skin Phenotype in Systemic Sclerosis.

空间 WNT 激活紊乱——系统性硬化症网状皮肤表型的潜在驱动因素

期刊:Arthritis & Rheumatology
影响因子:10.9
doi:10.1002/art.43094
Fakhouri Sara Chenguiti, Zhu Honglin, Li Yi-Nan, Ronicke Moritz, Rigau Aleix Rius, Dees Clara, Konstantinidis Laura, Schmid Ralf, Matei Alexandru-Emil, Eckstein Markus, Geppert Carol, Ludolph Ingo, Kreuter Alexander, Sticherling Michael, Berking Carola, Horch Raymund E, Schett Georg, Distler Jörg H W, Bergmann Christina
其它
空间多组学
发表日期：2025
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Combination therapies of porcupine inhibition with ruxolitinib, ibrutinib, or belumosudil in murine sclerodermatous GVHD

在小鼠硬皮病型移植物抗宿主病中，刺猬蛋白抑制剂与鲁索替尼、伊布替尼或贝鲁莫舒地尔联合治疗的疗效

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2024014387
Hong, Xuezhi; Xiao, Yanhua; Xu, Liyan; Shen, Lichong; Neelagar, Ranjana; Devakumar, Veda; Trinh-Minh, Thuong; Liang, Minrui; Rius Rigau, Aleix; Zhang, Yun; Li, Yi-Nan; Dees, Clara; Györfi, Andrea-Hermina; Wolff, Daniel; Herr, Wolfgang; Schett, Georg; Distler, Jörg H W; Matei, Alexandru-Emil
系统性硬化症
发表日期：2025
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Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis

非经典WNT5A控制潜伏型TGF-β的激活，从而驱动成纤维细胞活化和组织纤维化。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI159884
Trinh-Minh, Thuong; Chen, Chih-Wei; Tran Manh, Cuong; Li, Yi-Nan; Zhu, Honglin; Zhou, Xiang; Chakraborty, Debomita; Zhang, Yun; Rauber, Simon; Dees, Clara; Lin, Neng-Yu; Kah, Delf; Gerum, Richard; Bergmann, Christina; Kreuter, Alexander; Reuter, Christiane; Groeber-Becker, Florian; Eckes, Beate; Distler, Oliver; Fabry, Ben; Ramming, Andreas; Schambony, Alexandra; Schett, Georg; Distler, Jörg Hw
TGF-β
成纤维细胞
细胞生物学
WNT5A
发表日期：2024
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Assessment of myocardial fibrosis in patients with systemic sclerosis using [(68)Ga]Ga-FAPI-04-PET-CT

利用[(68)Ga]Ga-FAPI-04-PET-CT评估系统性硬化症患者的心肌纤维化

期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:7.6
doi:10.1007/s00259-022-06081-4
Treutlein, Christoph; Distler, Jörg H W; Tascilar, Koray; Fakhouri, Sara Chenguiti; Györfi, Andrea-Hermina; Atzinger, Armin; Matei, Alexandru-Emil; Dees, Clara; Büttner-Herold, Maike; Kuwert, Torsten; Prante, Olaf; Bäuerle, Tobias; Uder, Michael; Schett, Georg; Schmidkonz, Christian; Bergmann, Christina
FAP
系统性硬化症
免疫/内分泌
发表日期：2023
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β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

β-catenin是系统性硬化症中促纤维化Wnt信号通路的核心介质

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2011-200568
Beyer, Christian; Schramm, Amelie; Akhmetshina, Alfiya; Dees, Clara; Kireva, Trayana; Gelse, Kolja; Sonnylal, Sonali; de Crombrugghe, Benoit; Taketo, Makoto Mark; Distler, Oliver; Schett, Georg; Distler, Jörg H W
信号转导
Wnt/β-Catenin
系统性硬化症
免疫/内分泌
发表日期：2012
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Platelet-derived serotonin links vascular disease and tissue fibrosis.

血小板衍生的血清素将血管疾病与组织纤维化联系起来

期刊:Journal of Experimental Medicine
影响因子:10.6
doi:10.1084/jem.20101629
Dees Clara, Akhmetshina Alfiya, Zerr Pawel, Reich Nicole, Palumbo Katrin, Horn Angelika, Jüngel Astrid, Beyer Christian, Krönke Gerhard, Zwerina Jochen, Reiter Rudolf, Alenina Natalia, Maroteaux Luc, Gay Steffen, Schett Georg, Distler Oliver, Distler Jörg H W
其它
血管生成
发表日期：2011
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Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts

微粒通过诱导滑膜成纤维细胞中的ELR(+) CXC趋化因子来刺激血管生成

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/j.1582-4934.2010.01051.x
Reich, Nicole; Beyer, Christian; Gelse, Kolja; Akhmetshina, Alfiya; Dees, Clara; Zwerina, Jochen; Schett, Georg; Distler, Oliver; Distler, Jörg H W
成纤维细胞
细胞生物学
血管生成
免疫/内分泌
发表日期：2011
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Lack of inhibitory effects of the anti-fibrotic drug imatinib on endothelial cell functions in vitro and in vivo

抗纤维化药物伊马替尼在体外和体内均未显示出对内皮细胞功能的抑制作用

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/j.1582-4934.2008.00492.x
Venalis, Paulius; Maurer, Britta; Akhmetshina, Alfiya; Busch, Nicole; Dees, Clara; Stürzl, Michael; Zwerina, Jochen; Jüngel, Astrid; Gay, Steffen; Schett, Georg; Distler, Oliver; Distler, Jörg H W
细胞生物学
内皮细胞
发表日期：2009
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