Defang Li相关文献与解析，生知库 | 链接生命科学的每一步

Liu, Yiran; Zhang, Qiang; Qi, Ying; Wan, Teng; Zhang, Defang; Li, Yutong; Zhang, Xin; Ma, Longbin; Ruan, Qiuyue; Guo, Huanting; Li, Yingchun; Miao, Xinyue; Xiao, Wenjun; Li, Yongbo; Yuan, Jiang; Chen, Shanxiong

发表日期：2025

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Dietary Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether (BDE-47) Causes Inflammation in the Liver of Common Carp (Cyprinus carpio) and Affects Lipid Metabolism by Interfering with Steroid Hormone Biosynthesis Pathways

膳食中接触2,2',4,4'-四溴二苯醚（BDE-47）会导致鲤鱼（Cyprinus carpio）肝脏炎症，并通过干扰类固醇激素生物合成途径影响脂质代谢。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms262010152

Chen, Shuhuang; Han, Nian; Huang, Yujie; Sun, Huimin; Liu, Youlian; Chen, Defang; Li, Zhiqiong; Zhang, Xin

炎症

炎症/感染

Immunology/Inflammation

Exploration of Appetite Regulation in Yangtze Sturgeon (Acipenser dabryanus) During Weaning

长江鲟（Acipenser dabryanus）断奶期间食欲调节的研究

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26030950

Wang, Bin; Tang, Ni; Chen, Shuhuang; Zhang, Xin; Chen, Defang; Li, Zhiqiong; Zhou, Bo

发表日期：2025

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Emergence of linezolid-resistant Enterococcus cecorum clade F harboring optrA/fexA causing enterococcal spondylitis in commercial broilers in China

中国商业肉鸡中出现携带optrA/fexA基因的耐利奈唑胺盲肠球菌F分支，引起肠球菌性脊柱炎。

期刊:BMC Microbiology

影响因子:4.2

doi:10.1186/s12866-025-04045-w

Meng, Fanrun; Zhou, Defang; Li, Ruiqi; Lang, Feng; Xiang, Bin; Yang, Liangyu; Cheng, Ziqiang

发表日期：2025

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Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis

Bombinin-BO1 通过 HSP90A-Cdc37-CDK1 轴诱导肝细胞癌细胞周期停滞和细胞凋亡

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2024.110382

Xiaoting Wang, Peiyu Tang, Yitong Gong, Hang Yao, Mingpeng Liang, Hongxia Qu, Xiao Han, Qiusheng Zheng, Zhen Shi, Defang Li, Qingling Jiang

Farrerol suppresses osteoclast differentiation and postmenopausal osteoporosis by inhibiting the nuclear factor kappa B signaling pathway

Farrerol 通过抑制核因子 κB 信号通路抑制破骨细胞分化和绝经后骨质疏松症

期刊:Journal of Pharmacological Sciences

影响因子:3

doi:10.1016/j.jphs.2023.12.011

Wei Lu, Guobin Qi, Xiuying Yang, Defang Li, Weibin Chen, Qingmin Zeng, Zengxin Jiang

Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis

抗maRCO mAb调节肿瘤相关巨噬细胞极化通过调节骨肉瘤细胞增殖、迁移和凋亡发挥抗骨肉瘤作用

期刊:Journal of Orthopaedic Surgery and Research

影响因子:2.8

doi:10.1186/s13018-024-04950-2

Lei Ding #, Ling Wu #, Yuting Cao #, Hao Wang, Defang Li, Weibin Chen, Ping Huang, Zengxin Jiang

Targeting HSP90 with picropodophyllin suppresses gastric cancer tumorigenesis by disrupting the association of HSP90 and AKT

利用鬼臼苦素靶向 HSP90 可破坏 HSP90 与 AKT 的结合，从而抑制胃癌肿瘤发生

期刊:Phytotherapy Research

影响因子:6.1

doi:10.1002/ptr.7943

Xiaoli Li, Guoli Wang, Xiaolin Zhou, Huijie Zhao, Xiaojie Chen, Qixiao Cui, Minjing Li, Xihang Gao, Xiaoyu Wei, Lei Ye, Defang Li, Pan Hong

The abrogation of GRP78 sensitizes liver cancer cells to lysionotin by enhancing ER stress-mediated pro-apoptotic pathway

GRP78 的消除通过增强内质网应激介导的促凋亡途径使肝癌细胞对溶菌素敏感

期刊:Cell Stress & Chaperones

影响因子:3.3

doi:10.1007/s12192-023-01358-5

Ying Zou #, Hewen Shi #, Haiyan Lin #, Xiaoxue Wang, Guoli Wang, Yijia Gao, Fan Yi, Yancun Yin, Defang Li, Minjing Li

Gamabufotalin Induces Apoptosis and Cytoprotective Autophagy through the mTOR Signaling Pathway in Hepatocellular Carcinoma

蟾蜍灵通过 mTOR 信号通路诱导肝细胞癌细胞凋亡和细胞保护性自噬

期刊:Journal of Natural Products

影响因子:3.3

doi:10.1021/acs.jnatprod.2c01155

Ling Liu, Dan Shi, Zi-Yi Xia, Bo-Wen Wang, Xue-Li Wang, Xiao-Ting Wang, Guo-Li Wang, Min-Jing Li, Qiu-Sheng Zheng, Defang Li, Bo-Han Li

DeepJiandu Dataset for Character Detection and Recognition on Jiandu Manuscript

DeepJiandu 数据集用于建都手稿上的字符检测和识别

Dietary Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether (BDE-47) Causes Inflammation in the Liver of Common Carp (Cyprinus carpio) and Affects Lipid Metabolism by Interfering with Steroid Hormone Biosynthesis Pathways

膳食中接触2,2',4,4'-四溴二苯醚（BDE-47）会导致鲤鱼（Cyprinus carpio）肝脏炎症，并通过干扰类固醇激素生物合成途径影响脂质代谢。

Exploration of Appetite Regulation in Yangtze Sturgeon (Acipenser dabryanus) During Weaning

长江鲟（Acipenser dabryanus）断奶期间食欲调节的研究

Emergence of linezolid-resistant Enterococcus cecorum clade F harboring optrA/fexA causing enterococcal spondylitis in commercial broilers in China

中国商业肉鸡中出现携带optrA/fexA基因的耐利奈唑胺盲肠球菌F分支，引起肠球菌性脊柱炎。

Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis

Bombinin-BO1 通过 HSP90A-Cdc37-CDK1 轴诱导肝细胞癌细胞周期停滞和细胞凋亡

Farrerol suppresses osteoclast differentiation and postmenopausal osteoporosis by inhibiting the nuclear factor kappa B signaling pathway

Farrerol 通过抑制核因子 κB 信号通路抑制破骨细胞分化和绝经后骨质疏松症

Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis

抗maRCO mAb调节肿瘤相关巨噬细胞极化通过调节骨肉瘤细胞增殖、迁移和凋亡发挥抗骨肉瘤作用

Targeting HSP90 with picropodophyllin suppresses gastric cancer tumorigenesis by disrupting the association of HSP90 and AKT

利用鬼臼苦素靶向 HSP90 可破坏 HSP90 与 AKT 的结合，从而抑制胃癌肿瘤发生

The abrogation of GRP78 sensitizes liver cancer cells to lysionotin by enhancing ER stress-mediated pro-apoptotic pathway

GRP78 的消除通过增强内质网应激介导的促凋亡途径使肝癌细胞对溶菌素敏感

Gamabufotalin Induces Apoptosis and Cytoprotective Autophagy through the mTOR Signaling Pathway in Hepatocellular Carcinoma

蟾蜍灵通过 mTOR 信号通路诱导肝细胞癌细胞凋亡和细胞保护性自噬