CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
CCR2 抑制可减少肿瘤髓系细胞并揭示检查点抑制剂的作用,从而减缓耐药性鼠类神经胶质瘤的进展
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1910856117
Joseph A Flores-Toro, Defang Luo, Adithya Gopinath, Matthew R Sarkisian, James J Campbell, Israel F Charo, Rajinder Singh, Thomas J Schall, Meenal Datta, Rakesh K Jain, Duane A Mitchell, Jeffrey K Harrison
信号转导
神经
肿瘤
胶质瘤
其它细胞
Functional/Block/Neutralize
Checkpoint
Mouse
PDCD1