Defu Zeng相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Engineering CpG island DNA methylation in pluripotent cells through synthetic CpG-free ssDNA insertion

通过合成的无CpG单链DNA插入，在多能干细胞中改造CpG岛DNA甲基化。

期刊:Cell Reports Methods

影响因子:4.3

doi:10.1016/j.crmeth.2023.100465

Joshua Tompkins ,Elizabeth Lizhar ,Alireza Shokrani ,Xiwei Wu ,Jordan Berley ,Diba Kamali ,Deborah Hussey ,Jonas Cerneckis ,Tae Hyuk Kang ,Jinhui Wang ,Walter Tsark ,Defu Zeng ,Swetha Godatha ,Rama Natarajan ,Arthur Riggs

发育与干细胞

细胞生物学

发表日期：2023

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microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function

microRNA-142 通过控制 Treg 细胞稳态和功能来预防自身免疫

期刊:PLoS Biology

影响因子:7.8

doi:10.1371/journal.pbio.3001552

Wei-Le Wang, Ching Ouyang, Natalie M Graham, Yuankun Zhang, Kaniel Cassady, Estefany Y Reyes, Min Xiong, Alicia M Davis, Kathie Tang, Defu Zeng, Mark P Boldin

细胞生物学

发表日期：2022

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Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity

耐受性抗 IL-2 mAb 可预防移植物抗宿主病，同时保留强大的移植物抗白血病活性

影响因子:21

doi:10.1182/blood.2020006345

Qingxiao Song, Xiaoning Wang, Xiwei Wu, Hanjun Qin, Yingfei Li, Arthur D Riggs, Paul J Martin, Yuan-Zhong Chen, Defu Zeng

发表日期：2021

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IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

IL-22 依赖性菌群失调和单核吞噬细胞耗竭导致小鼠类固醇耐药性肠道移植物抗宿主病

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-21133-3

Qingxiao Song, Xiaoning Wang, Xiwei Wu, Tae Hyuk Kang, Hanjun Qin, Dongchang Zhao, Robert R Jenq, Marcel R M van den Brink, Arthur D Riggs, Paul J Martin, Yuan-Zhong Chen, Defu Zeng

细胞生物学

发表日期：2021

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Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

滤泡外CD4+结核分枝杆菌的相互作用足以诱发自身免疫样慢性移植物抗宿主病。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-017-00880-2

Ruishu Deng ，Christian Hurtz ，Qingxiao Song ，Chanyu Yue ，Gang Xiao ，Hua Yu ，Xiwei Wu ，Markus Muschen ，Stephen Forman ，Paul J Martin ，Defu Zeng

免疫/内分泌

发表日期：2017

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MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

MHC 不匹配的混合嵌合体增强了胸腺调节性 T 细胞的产生并防止小鼠 EAE 复发

期刊:Proceedings of the National Academy of Sciences of the United States of America

doi:10.1073/pnas.1521157112

Limin Wu, Nainong Li, Mingfeng Zhang, Sheng-Li Xue, Kaniel Cassady, Qing Lin, Arthur D Riggs, Defu Zeng

细胞生物学

发表日期：2015

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Host APCs augment in vivo expansion of donor natural regulatory T cells via B7H1/B7.1 in allogeneic recipients

宿主 APC 通过 B7H1/B7.1 增强同种异体受体中供体天然调节性 T 细胞的体内扩增

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1002939

Tangsheng Yi, Xiaofan Li, Sheng Yao, Lin Wang, Yuhong Chen, Dongchang Zhao, Heather F Johnston, James S Young, Hongjun Liu, Ivan Todorov, Stephen J Forman, Lieping Chen, Defu Zeng

细胞生物学

T Cell Receptor

发表日期：2011

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Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease

同种免疫反应导致移植物中自身反应性供体 CD4+ T 细胞扩增，从而可介导慢性移植物抗宿主病

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1002195

Dongchang Zhao, James S Young, Yu-Hong Chen, Elizabeth Shen, Tangsheng Yi, Ivan Todorov, Peiguo G Chu, Stephen J Forman, Defu Zeng

细胞生物学

发表日期：2011

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Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI

抗 CD3 预处理可通过调节 TBI 受体中的宿主树突状细胞和供体 T 细胞迁移来区分 GVL 与 GVHD

影响因子:21

doi:10.1182/blood-2008-06-165522

Nainong Li, Ying Chen, Wei He, Tangsheng Yi, Dongchang Zhao, Chunyan Zhang, Chia-Lei Lin, Ivan Todorov, Fouad Kandeel, Stephen Forman, Defu Zeng

细胞生物学

树突状细胞

T Cell Receptor

发表日期：2009

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IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

IL-17 可通过 IL-6-Stat3 信号通路促进肿瘤生长

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20090207

Lin Wang, Tangsheng Yi, Marcin Kortylewski, Drew M Pardoll, Defu Zeng, Hua Yu

发表日期：2009

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