日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pathogenic Genomic Alterations in Circulating Tumor DNA Predict Overall Survival in Men with Metastatic Castrate-resistant Prostate Cancer

循环肿瘤DNA中的致病性基因组改变可预测转移性去势抵抗性前列腺癌患者的总生存期

Halabi, Susan; Guo, Siyuan; Luo, Bin; Yu, Chenxi; Knutson, Todd P; Kobilka, Anna; Lyman, Jacqueline; Beltran, Himisha; Antonarakis, Emmanuel S; Galsky, Matthew D; Rosenberg, Jonathan E; Ryan, Charles J; Small, Eric J; Kelly, W Kevin; Morris, Michael J; Page, David; Dehm, Scott M; Armstrong, Andrew J

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer

CREB5 调控干细胞样转录程序,从而促进前列腺癌的肿瘤进展

Makovec, Allison; Phoenix, John T; Bergom, Hannah E; Boytim, Ella; Gustafson, Ava P; Deacon, Aiden; Tape, Sydney; Ali, Atef; Ludwig, Megan; Pitzen, Samuel P; Moline, David; Richter, Camden; Longie, Hudson; Su, Mei-Chi; Jena, Sampreeti; Likasitwatanakul, Pornlada; Drake, Justin M; Huang, R Stephanie; Hahn, William C; Rennhack, Jonathan P; Dehm, Scott M; Kregel, Steven; Antonarakis, Emmanuel S; Hwang, Justin

Proteomic Profiling of Extracellular Vesicles Distinguishes Prostate Cancer Molecular Subtypes

细胞外囊泡蛋白质组学分析可区分前列腺癌分子亚型

Ludwig, Megan L; Arafa, Ali T; Vinoo, Saasha; Jones, Jason C; Day, Abderrahman; Bergom, Hannah E; Sychev, Zoi; Horrmann, Alec; Levinson, Nicholas M; Dehm, Scott M; Antonarakis, Emmanuel S; Hwang, Justin; Drake, Justin M

Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes

基于结构导向的FOXA1改变分类可识别具有相反临床结果和不同分子及免疫学亚型的前列腺癌

Hwang, Justin; Likasitwatanakul, Pornlada; Deshmukh, Sachin Kumar; Wu, Sharon; Kwon, Jason J; Toye, Eamon; Moline, David; Evans, Mark G; Elliott, Andrew; Passow, Rachel; Luo, Christine; John, Emily; Gandhi, Nishant; McKay, Rana R; Heath, Elisabeth I; Nabhan, Chadi; Reizine, Natalie; Orme, Jacob J; Domingo Domenech, Josep M; Sartor, Oliver; Baca, Sylvan C; Dehm, Scott M; Antonarakis, Emmanuel S

Germline-Somatic Interactions in BRCA-Associated Cancers: Unique Molecular Profiles and Clinical Outcomes Linking ATM to TP53 Synthetic Essentiality

BRCA相关癌症中的种系-体细胞相互作用:独特的分子特征和临床结果将ATM与TP53合成必需性联系起来

Arafa, Ali T; Yadav, Siddhartha; Marshall, Catherine H; Mauer, Elizabeth; Huang, Minxuan; Yilma, Binyam; van der Pol, Ymke; Fragkogianni, Stamatina; Teslow, Emily A; Kellen, Samuel; Boytim, Ella; Luo, Christine; Ludwig, Megan; Zhang, Weijie; Jayaraj, Arockia; Armstrong, Deborah K; Isaacs, William B; Drake, Justin M; Nguyen, Hai Dang; Huang, R Stephanie; Chao, Calvin Y; Lou, Emil; Dehm, Scott M; Couch, Fergus J; Hwang, Justin H; Antonarakis, Emmanuel S

Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer

比较转录组学揭示去势抵抗性前列腺癌中混合的基底细胞、棒状细胞和丘状细胞上皮细胞特性

Pitzen, Samuel P; Rudenick, Amber N; Qiu, Yinjie; Zhang, Weijie; Munro, Sarah A; McCluskey, Braedan M; Forster, Colleen; Bergom, Hannah E; Ali, Atef; Boytim, Ella; Lafin, John T; Linder, Simon; Ismail, Mazlina; Devlies, Wout; Sessions, Conner J; Claessens, Frank; Joniau, Steven; Attard, Gerhardt; Zwart, Wilbert; Nelson, Peter S; Corey, Eva; Wang, Yuzhuo; Lang, Joshua M; Beltran, Himisha; Strand, Douglas; Antonarakis, Emmanuel S; Hwang, Justin; Murugan, Paari; Huang, R Stephanie; Dehm, Scott M

SFPQ subcellular mislocalisation entails altered cancer cell function

SFPQ亚细胞定位异常会导致癌细胞功能改变。

Yang, Libang; Gilbertsen, Adam; Jacobson, Blake; Kratzke, Robert; Li, Yingming; Sun, Bo; Karam, Sabine; Dehm, Scott M; Henke, Craig A

Novel Mixed Cancer-Cell Models Designed to Capture Inter-Patient Tumor Heterogeneity for Accurate Evaluation of Drug Combinations

新型混合癌细胞模型旨在捕捉患者间肿瘤异质性,从而准确评估药物组合

Jena, Sampreeti; Kim, Daniel C; Lee, Adam M; Zhang, Weijie; Zhan, Kevin; Elmorsi, Radwa M; Li, Yingming; Dehm, Scott M; Huang, R Stephanie

Systems-level liquid biopsy in advanced prostate cancer

晚期前列腺癌的系统级液体活检

Lyman, Jacqueline; Dehm, Scott M

Adverse prognosis gene expression patterns in metastatic castration-resistant prostate cancer

转移性去势抵抗性前列腺癌的不良预后基因表达模式

Sharifi, Marina N; Feng, Eric; Rydzewski, Nicholas R; Taylor, Amy K; Sperger, Jamie M; Shi, Yue; Helzer, Kyle T; Bootsma, Matthew L; Carreno, Viridiana; Chang, Alex H; Nunamaker, Luke A; Blitzer, Grace C; Shang, Tianfu Andy; Subramanian, Aishwarya; Bjartell, Anders; Josefsson, Andreas; Wikström, Pernilla; Feng, Emily; Kohli, Manish; Yang, Rendong; Dehm, Scott M; Small, Eric J; Aggarwal, Rahul; Quigley, David A; Lang, Joshua M; Zhao, Shuang G; Sjöström, Martin