Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia
RAS通路激活介导的克隆选择导致急性髓系白血病对选择性FLT3抑制剂产生继发性临床耐药性
期刊:Cancer Discovery
影响因子:33.3
doi:10.1158/2159-8290.CD-18-1453
McMahon, Christine M; Ferng, Timothy; Canaani, Jonathan; Wang, Eunice S; Morrissette, Jennifer J D; Eastburn, Dennis J; Pellegrino, Maurizio; Durruthy-Durruthy, Robert; Watt, Christopher D; Asthana, Saurabh; Lasater, Elisabeth A; DeFilippis, RosaAnna; Peretz, Cheryl A C; McGary, Lisa H F; Deihimi, Safoora; Logan, Aaron C; Luger, Selina M; Shah, Neil P; Carroll, Martin; Smith, Catherine C; Perl, Alexander E