日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A proof-of-mechanism trial in asthma with lunsekimig, a bispecific NANOBODY molecule

一项针对哮喘的机制验证试验,研究了双特异性纳米抗体分子lunsekimig的作用机制。

Deiteren, Annemie; Krupka, Emmanuel; Bontinck, Lieselot; Imberdis, Karine; Conickx, Griet; Bas, Selcuk; Patel, Naimish; Staudinger, Heribert W; Suratt, Benjamin T

A first-in-human, single and multiple dose study of lunsekimig, a novel anti-TSLP/anti-IL-13 NANOBODY® compound, in healthy volunteers

一项针对健康志愿者的首次人体单次和多次给药研究,评估了新型抗TSLP/抗IL-13纳米抗体®化合物lunsekimig的疗效。

Deiteren, Annemie; Bontinck, Lieselot; Conickx, Griet; Vigan, Marie; Dervaux, Nele; Gassiot, Matthieu; Bas, Selcuk; Suratt, Benjamin; Staudinger, Heribert; Krupka, Emmanuel

Using a wearable patch to develop a digital monitoring biomarker of inflammation in response to LPS challenge

利用可穿戴贴片开发一种数字监测生物标志物,用于检测LPS刺激引起的炎症反应。

Avey, Stefan; Chatterjee, Meenakshi; Manyakov, Nikolay V; Cooper, Philip; Sabins, Nina; Mosca, Kenneth; Mori, Simone; Baribaud, Frédéric; Morris, Mark; Lehar, Joseph; Deiteren, Annemie; Cossu, Marta; Smets, Sophie; Huizer, Tanja; Lamousé-Smith, Esi; Campbell, Kim; Pandis, Ioannis

A novel haemocytometric COVID-19 prognostic score developed and validated in an observational multicentre European hospital-based study

一项基于欧洲多中心医院的观察性研究开发并验证了一种新型血细胞计数 COVID-19 预后评分。

Linssen, Joachim; Ermens, Anthony; Berrevoets, Marvin; Seghezzi, Michela; Previtali, Giulia; van der Sar-van der Brugge, Simone; Russcher, Henk; Verbon, Annelies; Gillis, Judith; Riedl, Jürgen; de Jongh, Eva; Saker, Jarob; Münster, Marion; Munnix, Imke Ca; Dofferhof, Anthonius; Scharnhorst, Volkher; Ammerlaan, Heidi; Deiteren, Kathleen; Bakker, Stephan Jl; Van Pelt, Lucas Joost; Kluiters-de Hingh, Yvette; Leers, Mathie Pg; van der Ven, Andre J

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

α-芋螺毒素Vc1.1的环状类似物可抑制结肠伤害感受器,并在慢性腹痛小鼠模型中发挥镇痛作用

Castro, Joel; Grundy, Luke; Deiteren, Annemie; Harrington, Andrea M; O'Donnell, Tracey; Maddern, Jessica; Moore, Jessi; Garcia-Caraballo, Sonia; Rychkov, Grigori Y; Yu, Rilei; Kaas, Quentin; Craik, David J; Adams, David J; Brierley, Stuart M

NaV1.1 inhibition can reduce visceral hypersensitivity

NaV1.1抑制可降低内脏高敏感性

Salvatierra, Juan; Castro, Joel; Erickson, Andelain; Li, Qian; Braz, Joao; Gilchrist, John; Grundy, Luke; Rychkov, Grigori Y; Deiteren, Annemie; Rais, Rana; King, Glenn F; Slusher, Barbara S; Basbaum, Allan; Pasricha, Pankaj J; Brierley, Stuart M; Bosmans, Frank

Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction

长期使用利那洛肽治疗可减少结肠炎引起的神经可塑性并逆转持续性膀胱功能障碍

Grundy, Luke; Harrington, Andrea M; Castro, Joel; Garcia-Caraballo, Sonia; Deiteren, Annemie; Maddern, Jessica; Rychkov, Grigori Y; Ge, Pei; Peters, Stefanie; Feil, Robert; Miller, Paul; Ghetti, Andre; Hannig, Gerhard; Kurtz, Caroline B; Silos-Santiago, Inmaculada; Brierley, Stuart M

Voltage-gated sodium channels: (Na(V) )igating the field to determine their contribution to visceral nociception

电压门控钠通道:(Na(V)) 检测场以确定其对内脏伤害感受的贡献

Erickson, Andelain; Deiteren, Annemie; Harrington, Andrea M; Garcia-Caraballo, Sonia; Castro, Joel; Caldwell, Ashlee; Grundy, Luke; Brierley, Stuart M

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments

体外记录小鼠空肠和结肠节段的肠系膜传入神经活动

Nullens, Sara; Deiteren, Annemie; Jiang, Wen; Keating, Christopher; Ceuleers, Hannah; Francque, Sven; Grundy, David; De Man, Joris G; De Winter, Benedicte Y

Histamine H₄ receptors in the gastrointestinal tract

胃肠道中的组胺H₄受体

Deiteren, A; De Man, J G; Pelckmans, P A; De Winter, B Y