日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The TLR7 agonist vesatolimod does not measurably induce SIV expression in macaques receiving combination antiretroviral therapy initiated during chronic infection

TLR7激动剂vesatolimod在接受慢性感染期间开始的联合抗逆转录病毒疗法的猕猴中,不能显著诱导SIV表达。

Swanstrom, Adrienne E; Oswald, Kelli; Fast, Randy; Shoemaker, Rebecca; Thomas, James A; Pyle, Cathi; Hull, Michael; Bosche, William J; Li, Yuan; Breed, Matthew W; Kramer, Joshua A; Donohue, Duncan; Trubey, Charles M; Deleage, Claire; Geleziunas, Romas; Lifson, Jeffrey D; Del Prete, Gregory Q

No evidence for ongoing replication on ART in SIV-infected macaques

没有证据表明SIV感染的猕猴在接受抗逆转录病毒治疗期间病毒仍在持续复制。

Immonen, Taina T; Fennessey, Christine M; Lipkey, Leslie; Newman, Laura; Macairan, Agatha; Bosche, Marjorie; Waltz, Nora; Del Prete, Gregory Q; Lifson, Jeffrey D; Keele, Brandon F

Tissue-Specific DNA Methylation Changes in CD8(+) T Cells During Chronic Simian Immunodeficiency Virus Infection of Infant Rhesus Macaques

幼年恒河猴慢性猴免疫缺陷病毒感染期间CD8(+) T细胞的组织特异性DNA甲基化变化

Nag, Mukta; Fogle, Jonathan E; Pillay, Santhoshan; Del Prete, Gregory Q; De Paris, Kristina

Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication

抗逆转录病毒疗法的启动时机可预测治疗后SIV复制的控制情况。

Pinkevych, Mykola; Docken, Steffen S; Okoye, Afam A; Fennessey, Christine M; Del Prete, Gregory Q; Pino, Maria; Harper, Justin L; Betts, Michael R; Paiardini, Mirko; Keele, Brandon F; Davenport, Miles P

Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir

在感染SIV的猕猴中,分析治疗中断期间的短暂病毒复制可能会改变具有反弹能力的病毒库。

Immonen, Taina T; Fennessey, Christine M; Lipkey, Leslie; Thorpe, Abigail; Del Prete, Gregory Q; Lifson, Jeffrey D; Davenport, Miles P; Keele, Brandon F

Genetically barcoded SIV reveals the emergence of escape mutations in multiple viral lineages during immune escape.

通过基因条形码标记的SIV揭示了免疫逃逸过程中多个病毒谱系中逃逸突变的出现

Immonen Taina T, Camus Celine, Reid Carolyn, Fennessey Christine M, Del Prete Gregory Q, Davenport Miles P, Lifson Jeffrey D, Keele Brandon F

The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections

接受抗逆转录病毒疗法治疗的SIV、SHIV和HIV-2感染中持续存在的病毒基因组概况

Bender, Alexandra M; Simonetti, Francesco R; Kumar, Mithra R; Fray, Emily J; Bruner, Katherine M; Timmons, Andrew E; Tai, Katherine Y; Jenike, Katharine M; Antar, Annukka A R; Liu, Po-Ting; Ho, Ya-Chi; Raugi, Dana N; Seydi, Moussa; Gottlieb, Geoffrey S; Okoye, Afam A; Del Prete, Gregory Q; Picker, Louis J; Mankowski, Joseph L; Lifson, Jeffrey D; Siliciano, Janet D; Laird, Greg M; Barouch, Dan H; Clements, Janice E; Siliciano, Robert F

Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host

从嗜猴HIV-1感染性克隆中分离得到病毒,揭示了病毒对新宿主的适应性

Schmidt, Fabian; Keele, Brandon F; Del Prete, Gregory Q; Voronin, Dennis; Fennessey, Christine M; Soll, Steven; Kane, Melissa; Raymond, Alice; Gifford, Robert J; KewalRamani, Vineet; Lifson, Jeffrey D; Bieniasz, Paul D; Hatziioannou, Theodora

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

接受抗逆转录病毒疗法的猕猴体内SIV感染细胞的克隆扩增与人类HIV感染细胞的克隆扩增相似。

Ferris, Andrea L; Wells, David W; Guo, Shuang; Del Prete, Gregory Q; Swanstrom, Adrienne E; Coffin, John M; Wu, Xiaolin; Lifson, Jeffrey D; Hughes, Stephen H

Evaluating the Intactness of Persistent Viral Genomes in Simian Immunodeficiency Virus-Infected Rhesus Macaques after Initiating Antiretroviral Therapy within One Year of Infection

评估感染猴免疫缺陷病毒后一年内开始抗逆转录病毒治疗后,恒河猴体内持续存在的病毒基因组的完整性

Long, Samuel; Fennessey, Christine M; Newman, Laura; Reid, Carolyn; O'Brien, Sean P; Li, Yuan; Del Prete, Gregory Q; Lifson, Jeffrey D; Gorelick, Robert J; Keele, Brandon F