日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function

一种专门设计的多益生菌制剂可减少尿毒症毒素的产生并改善肾功能。

Beau, Alice; Natividad, Jane; Benoit, Berengère; Delerive, Philippe; Duboux, Stéphane; Feng, Yuan; Jammes, Marie; Barnel, Cecile; Sequino, Giuseppina; Pinteur, Claudie; Glorieux, Griet; Fouque, Denis; Vidal, Hubert; Koppe, Laetitia

Covalent Inhibitors of KEAP1 with Exquisite Selectivity.

具有极高选择性的KEAP1共价抑制剂

Fejes Imre, Markacz Piroska, Tatai Janos, Rudas Monika, Dunkel Petra, Gyuris Mario, Nyerges Miklos, Provost Nicolas, Duvivier Valérie, Delerive Philippe, Martiny Virginie, Bristiel Alexandra, Vidal Brice, Richardson William, Rothweiler Elisabeth M, Tranberg-Jensen Jeppe, Manning Charlotte E, Sweeney Melissa N, Chalk Rod, Huber Kilian V M, Bullock Alex N, Herner Andras, Seedorf Klaus, Vinson Cedric, Weber Csaba, Kotschy Andras

Long-term use of investigational β-Hydroxybutyrate salts in children with multiple acyl-CoA dehydrogenase or pyruvate dehydrogenase deficiency

在患有多种酰基辅酶A脱氢酶或丙酮酸脱氢酶缺乏症的儿童中,长期使用研究性β-羟基丁酸盐的研究

Morris, Andrew A M; Cuenoud, Bernard; Delerive, Philippe; Mundy, Helen; Schwahn, Bernd C

A new NRF2 activator for the treatment of human metabolic dysfunction-associated fatty liver disease.

一种用于治疗人类代谢功能障碍相关脂肪肝疾病的新型 NRF2 激活剂

Hammoutene Adel, Laouirem Samira, Albuquerque Miguel, Colnot Nathalie, Brzustowski Angélique, Valla Dominique, Provost Nicolas, Delerive Philippe, Paradis Valérie

Characterization and Pharmacological Validation of a Preclinical Model of NASH in Göttingen Minipigs

哥廷根小型猪非酒精性脂肪性肝炎临床前模型的特征分析和药理学验证

Duvivier, Valérie; Creusot, Stéphanie; Broux, Olivier; Helbert, Aurélie; Lesage, Ludovic; Moreau, Kevin; Lesueur, Nicolas; Gerard, Lindsay; Lemaitre, Karine; Provost, Nicolas; Hubert, Edwige-Ludiwyne; Baltauss, Tania; Brzustowski, Angelique; De Preville, Nathalie; Geronimi, Julia; Adoux, Lucie; Letourneur, Franck; Hammoutene, Adel; Valla, Dominique; Paradis, Valérie; Delerive, Philippe

Procollagen C-Proteinase Enhancer-1 (PCPE-1) deficiency in mice reduces liver fibrosis but not NASH progression

小鼠前胶原 C 蛋白酶增强剂-1 (PCPE-1) 缺乏可减轻肝纤维化,但不会减轻 NASH 进展

Patricia Sansilvestri Morel, Valerie Duvivier, Florence Bertin, Nicolas Provost, Adel Hammoutene, Edwige-Ludiwyne Hubert, Arantxa Gonzalez, Isabelle Tupinon-Mathieu, Valerie Paradis, Philippe Delerive

Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

活体人类胰岛供体的多组学分析揭示了异质性 β 细胞向 2 型糖尿病发展的轨迹

Leonore Wigger #, Marko Barovic #, Andreas-David Brunner #, Flavia Marzetta, Eyke Schöniger, Florence Mehl, Nicole Kipke, Daniela Friedland, Frederic Burdet, Camille Kessler, Mathias Lesche, Bernard Thorens, Ezio Bonifacio, Cristina Legido-Quigley, Pierre Barbier Saint Hilaire, Philippe Delerive, An

MG53 is not a critical regulator of insulin signaling pathway in skeletal muscle

MG53 不是骨骼肌胰岛素信号通路的关键调节剂

Clothilde Philouze, Sophie Turban, Beatrice Cremers, Audrey Caliez, Gwladys Lamarche, Catherine Bernard, Nicolas Provost, Philippe Delerive

Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research.

对人类外周血单核细胞和代谢疾病研究中常用的替代单核细胞样细胞系进行比较基因型和表型分析

Riddy Darren M, Goy Emily, Delerive Philippe, Summers Roger J, Sexton Patrick M, Langmead Christopher J

Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic

发现和优化氮杂环丁烷系列化合物作为游离脂肪酸受体 2 (FFA2) 拮抗剂:从热门药物到临床

Mathieu Pizzonero, Sonia Dupont, Marielle Babel, Stéphane Beaumont, Natacha Bienvenu, Roland Blanqué, Laëtitia Cherel, Thierry Christophe, Benedetta Crescenzi, Elsa De Lemos, Philippe Delerive, Pierre Deprez, Steve De Vos, Fatoumata Djata, Stephen Fletcher, Sabrina Kopiejewski, Christelle L'Ebraly,