日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and ADHD

非典型DAT缺乏综合征的小鼠模型揭示了与帕金森病和ADHD相关的多巴胺功能障碍

Herborg, Freja; Konrad, Lisa K; Jørgensen, Søren H; Lilja, Jamila H; Delignat-Lavaud, Benoît; Posselt, Leonie P; Pugh, Ciara F; Bach, Sofie A; Ratner, Cecilia F; Awadallah, Nora; Pino, Jose A; Berlin, Frida; Ejdrup, Aske L; Olesen, Mikkel V; Rickhag, Mattias; Holst, Birgitte; Aznar, Susana; Mayer, Felix P; Woldbye, David; Torres, Gonzalo; Trudeau, Louis-Eric; Gether, Ulrik

Novel assays to assess the prevalence and neutralizing potential of anti-IdeS antibodies in healthy humans

用于评估健康人群中抗IdeS抗体的流行率和中和潜力的新型检测方法

Hannachi, Emna; Trecco, Amélia; Daventure, Victoria; Delignat, Sandrine; Bonilla, Perrine; Lecerf, Maxime; Thaunat, Olivier; Dimitrov, Jordan D; Deligne, Claire; Lacroix-Desmazes, Sébastien

Binding of therapeutic Fc-fused factor VIII to the neonatal Fc receptor at neutral pH associates with poor half-life extension

治疗性Fc融合因子VIII在中性pH条件下与新生儿Fc受体结合,导致半衰期延长效果不佳。

Alejandra Reyes-Ruiz,Sandrine Delignat,Aishwarya Sudam Bhale,Victoria Daventure,Robin V Lacombe,Leslie Dourthe,Olivier Christophe,Sune Justesen,Krishnan Venkataraman,Jordan D Dimitrov,Sebastien Lacroix-Desmazes

Regulation of immune responses to therapeutic factor VIII by transplacental delivery of Fc-fused immunodominant factor VIII domains or peptides

通过胎盘递送Fc融合的免疫优势因子VIII结构域或肽段来调节对治疗性因子VIII的免疫反应

Reyes-Ruiz, Alejandra; Delignat, Sandrine; Azam, Aurélien; Daventure, Victoria; Dourthe, Leslie; Mimoun, Angelina; McCluskey, Geneviève; Georgescu, Maria T; Lillicrap, David; Dimitrov, Jordan D; Lacroix-Desmazes, Sebastien

Half-Life Extension of the IgG-Degrading Enzyme (IdeS) Using Fc-Fusion Technology

使用 Fc-融合技术延长 IgG 降解酶 (IdeS) 的半衰期

Victoria Daventure, Melissa Bou-Jaoudeh, Emna Hannachi, Alejandra Reyes-Ruiz, Amélia Trecco, Sandrine Delignat, Sébastien Lacroix-Desmazes, Claire Deligne

Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice

突触结合蛋白-1依赖的阶段性轴突多巴胺释放对小鼠的基本运动行为是不必要的

Benoît Delignat-Lavaud, Jana Kano #, Charles Ducrot #, Ian Massé, Sriparna Mukherjee, Nicolas Giguère, Luc Moquin, Catherine Lévesque, Samuel Burke, Raphaëlle Denis, Marie-Josée Bourque, Alex Tchung, Pedro Rosa-Neto, Daniel Lévesque, Louis De Beaumont, Louis-Éric Trudeau

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice

IgG降解酶Imlifidase可恢复抑制剂阳性A型血友病小鼠体内FVIII的治疗活性。

Bou-Jaoudeh, Melissa; Delignat, Sandrine; Daventure, Victoria; Astermark, Jan; Lévesque, Hervé; Dimitrov, Jordan D; Deligne, Claire; Proulle, Valérie; Lacroix-Desmazes, Sébastien

Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats

向大鼠海马注射可溶性淀粉样β蛋白寡聚体可改变清醒和慢波睡眠期间的脑电活动

Audrey Hector, Chloé Provost, Benoît Delignat-Lavaud, Khadija Bouamira, Chahinez-Anissa Menaouar, Valérie Mongrain, Jonathan Brouillette

Conditional deletion of neurexins dysregulates neurotransmission from dopamine neurons

神经连接蛋白的条件性缺失导致多巴胺神经元的神经传递失调

Charles Ducrot, Gregory de Carvalho, Benoît Delignat-Lavaud, Constantin V L Delmas, Priyabrata Halder, Nicolas Giguère, Consiglia Pacelli, Sriparna Mukherjee, Marie-Josée Bourque, Martin Parent, Lulu Y Chen, Louis-Eric Trudeau

Implication of synaptotagmins 4 and 7 in activity-dependent somatodendritic dopamine release in the ventral midbrain

突触结合蛋白 4 和 7 对腹侧中脑活动依赖性体树突多巴胺释放的影响

Benoît Delignat-Lavaud, Charles Ducrot, Willemieke Kouwenhoven, Nina Feller, Louis-Éric Trudeau