IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease
肝巨噬细胞通过NLRP3炎症小体产生IL-1β,将丙型肝炎病毒感染与肝脏炎症和疾病联系起来。
期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1003330
Negash, Amina A; Ramos, Hilario J; Crochet, Nanette; Lau, Daryl T Y; Doehle, Brian; Papic, Neven; Delker, Don A; Jo, Juandy; Bertoletti, Antonio; Hagedorn, Curt H; Gale, Michael Jr
巨噬细胞
炎症
炎性小体
炎症/感染
巨噬细胞
微生物学
LRP3
NLRP3
IL-1β
细胞生物学
肝炎
炎性小体
免疫/内分泌