日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial

用于治疗杜氏肌营养不良症的AAV微型肌营养不良蛋白基因疗法:一项1b期试验

Butterfield, Russell J; Shieh, Perry B; Li, Huihua; Binks, Michael; McDonnell, Tara G; Ryan, Kelly A; Delnomdedieu, Marielle; Belluscio, Beth A; Neelakantan, Srividya; Levy, Daniel I; Schwartz, Pamela F; Smith, Edward C

Cardiac safety of fordadistrogene movaparvovec gene therapy in Duchenne muscular dystrophy: Initial observations from a phase 1b trial

杜氏肌营养不良症患者接受 fordadistrogene movaparvovec 基因治疗的心脏安全性:一项 1b 期试验的初步观察结果

Sherlock, Sarah P; Levy, Daniel I; McIntosh, Avery; Shieh, Perry B; Smith, Edward C; McDonnell, Tara G; Ryan, Kelly A; Delnomdedieu, Marielle; Binks, Michael; Lal, Ashwin K; Butterfield, Russell J

Complement activation in a phase Ib study of fordadistrogene movaparvovec for Duchenne muscular dystrophy

在针对杜氏肌营养不良症的 fordadistrogene movaparvovec 的 Ib 期研究中,补体激活

Byrne, Barry J; Butterfield, Russell J; Shieh, Perry B; Smith, Edward C; Licht, Christoph; Binks, Michael; Casinghino, Sandra; Delnomdedieu, Marielle; Ravindra, Kodihalli C; McDonnell, Tara; Ryan, Kelly; Schulz, Martin; Shen, Qi; Shi, Heliang; Sirivelu, Madhu P; Vaidya, Vishal S; Whiteley, Laurence; Levy, Daniel I

The D1/D5 Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson's Disease: A Feasibility Study

D1/D5多巴胺部分激动剂PF-06412562治疗晚期帕金森病:一项可行性研究

Huang, Xuemei; Lewis, Mechelle M; Van Scoy, Lauren Jodi; De Jesus, Sol; Eslinger, Paul J; Arnold, Amy C; Miller, Amanda J; Fernandez-Mendoza, Julio; Snyder, Bethany; Harrington, William; Kong, Lan; Wang, Xi; Sun, Dongxiao; Delnomdedieu, Marielle; Duvvuri, Sridhar; Mahoney, Susan E; Gray, David L; Mailman, Richard B

A Phase 2 clinical trial of PF-05212377 (SAM-760) in subjects with mild to moderate Alzheimer's disease with existing neuropsychiatric symptoms on a stable daily dose of donepezil

一项针对服用稳定剂量多奈哌齐且伴有神经精神症状的轻度至中度阿尔茨海默病患者的 PF-05212377 (SAM-760) II 期临床试验

Fullerton, Terence; Binneman, Brendon; David, William; Delnomdedieu, Marielle; Kupiec, James; Lockwood, Peter; Mancuso, Jessica; Miceli, Jeffrey; Bell, Joanne

First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheimer's disease

AAB-003 (PF-05236812) 在轻度至中度阿尔茨海默病患者中静脉输注递增剂量后的首次人体安全性和长期暴露数据及生物标志物

Delnomdedieu, Marielle; Duvvuri, Sridhar; Li, David Jianjun; Atassi, Nazem; Lu, Ming; Brashear, H Robert; Liu, Enchi; Ness, Seth; Kupiec, James W

Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo

舍曲林和安慰剂诱导的早期生化变化的药物代谢组学图谱

Kaddurah-Daouk, R; Bogdanov, M B; Wikoff, W R; Zhu, H; Boyle, S H; Churchill, E; Wang, Z; Rush, A J; Krishnan, R R; Pickering, E; Delnomdedieu, M; Fiehn, O

Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway

舍曲林和安慰剂治疗重度抑郁症的药物代谢组学研究——甲氧基吲哚途径的可能作用

Zhu, Hongjie; Bogdanov, Mikhail B; Boyle, Stephen H; Matson, Wayne; Sharma, Swati; Matson, Samantha; Churchill, Erik; Fiehn, Oliver; Rush, John A; Krishnan, Ranga R; Pickering, Eve; Delnomdedieu, Marielle; Kaddurah-Daouk, Rima