日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Description of Two Resistance-Nodulation-Cell Division Efflux Systems Involved in Acquired Antibiotic Resistance: AxySUV in Achromobacter xylosoxidans and AinCDJ in Achromobacter insuavis

对两种参与获得性抗生素耐药性的耐药-结节-细胞分裂外排系统进行描述:无色杆菌中的 AxySUV 和无色杆菌中的 AinCDJ

Magallon, Arnaud; Bador, Julien; Garrigos, Thomas; Demeule, Caroline; Chapelle, Anaïs; Varin, Véronique; Neuwirth, Catherine; Amoureux, Lucie

Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing

舒多西他赛 Zendusortide (TH1902) 可激活 cGAS/STING 通路并增强抗 PD-L1 免疫介导的肿瘤细胞杀伤作用

Michel Demeule ,Jean-Christophe Currie ,Cyndia Charfi ,Alain Zgheib ,Isabelle Cousineau ,Véronique Lullier ,Richard Béliveau ,Christian Marsolais ,Borhane Annabi

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution

单细胞多组学鉴定出慢性炎症是 TP53 突变白血病进化的驱动因素

Alba Rodriguez-Meira #, Ruggiero Norfo #, Sean Wen #, Agathe L Chédeville #, Haseeb Rahman, Jennifer O'Sullivan, Guanlin Wang, Eleni Louka, Warren W Kretzschmar, Aimee Paterson, Charlotte Brierley, Jean-Edouard Martin, Caroline Demeule, Matthew Bashton, Nikolaos Sousos, Daniela Moralli, Lamia Subha

The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells

TH1902 多西他赛肽药物偶联物抑制人类 SORT1 阳性卵巢癌和三阴性乳腺癌干细胞样细胞的异种移植生长

Michel Demeule, Cyndia Charfi, Jean-Christophe Currie, Alain Zgheib, Bogdan Alexandru Danalache, Richard Béliveau, Christian Marsolais, Borhane Annabi

The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers

肽-药物偶联物 TH1902:一种针对卵巢癌和子宫内膜癌的新型 Sortilin 受体介导癌症治疗方法

Jean-Christophe Currie, Michel Demeule, Cyndia Charfi, Alain Zgheib, Alain Larocque, Bogdan Alexandru Danalache, Amira Ouanouki, Richard Béliveau, Christian Marsolais, Borhane Annabi

TH1902, a new docetaxel-peptide conjugate for the treatment of sortilin-positive triple-negative breast cancer

TH1902,一种用于治疗分选蛋白阳性三阴性乳腺癌的新型多西他赛-肽结合物

Michel Demeule, Cyndia Charfi, Jean-Christophe Currie, Alain Larocque, Alain Zgheib, Sophie Kozelko, Richard Béliveau, Christian Marsolais, Borhane Annabi

New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells

新型肽-药物偶联物可精准靶向 TNBC 衍生的 MDA-MB-231 乳腺癌和卵巢 ES-2 透明细胞癌细胞的肿瘤微环境中的 SORT1 介导的血管生成拟态

Cyndia Charfi, Michel Demeule, Jean-Christophe Currie, Alain Larocque, Alain Zgheib, Bogdan Alexandru Danalache, Amira Ouanouki, Richard Béliveau, Christian Marsolais, Borhane Annabi

Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties

脑渗透肽与神经降压素的结合具有抗伤害作用

Michel Demeule, Nicolas Beaudet, Anthony Régina, Élie Besserer-Offroy, Alexandre Murza, Pascal Tétreault, Karine Belleville, Christian Ché, Alain Larocque, Carine Thiot, Richard Béliveau, Jean-Michel Longpré, Éric Marsault, Richard Leduc, Jean E Lachowicz, Steven L Gonias, Jean-Paul Castaigne, Phili

Assessment and significance of protein-protein interactions during development of protein biopharmaceuticals

蛋白质生物制药开发过程中蛋白质-蛋白质相互作用的评估及其意义

Yadav, Sandeep; Liu, Jun; Scherer, Thomas M; Gokarn, Yatin; Demeule, Barthélemy; Kanai, Sonoko; Andya, James D; Shire, Steven J

Weak interactions govern the viscosity of concentrated antibody solutions: high-throughput analysis using the diffusion interaction parameter

弱相互作用决定了浓缩抗体溶液的粘度:利用扩散相互作用参数进行高通量分析

Connolly, Brian D; Petry, Chris; Yadav, Sandeep; Demeule, Barthélemy; Ciaccio, Natalie; Moore, Jamie M R; Shire, Steven J; Gokarn, Yatin R