日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects

选择性鞘氨醇-1-磷酸亚型1受体激动剂对健康受试者皮层兴奋性的TMS和EEG药效学效应

de Cuba, Catherine M K E; de Goede, Annika A; Klaassen, Erica S; Otto, Marije E; Doll, Robert J; Kim, Jessica; Demitrack, Mark A; Chen, Ruihua; Groeneveld, Geert Jan; Heuberger, Jules A A C

A Multisite, 6-Month, Open-Label Study of Maintenance Transcranial Magnetic Stimulation for Adolescents with Treatment-Resistant Depression

一项针对难治性抑郁症青少年患者的多中心、6个月、开放标签的维持性经颅磁刺激研究

Garzon, Juan F; Elmaadawi, Ahmed Z; Aaronson, Scott T; Schrodt, G Randolph Jr; Holbert, Richard C; Zuckerman, Seth; Demitrack, Mark A; Strawn, Jeffrey R; Croarkin, Paul E

Neurostructural Differences in Adolescents With Treatment-Resistant Depression and Treatment Effects of Transcranial Magnetic Stimulation

难治性抑郁症青少年患者的神经结构差异及经颅磁刺激的治疗效果

Seewoo, Bhedita J; Rodger, Jennifer; Demitrack, Mark A; Heart, Karen L; Port, John D; Strawn, Jeffrey R; Croarkin, Paul E

Left prefrontal transcranial magnetic stimulation for treatment-resistant depression in adolescents: a double-blind, randomized, sham-controlled trial

左侧前额叶经颅磁刺激治疗青少年难治性抑郁症:一项双盲、随机、假刺激对照试验

Croarkin, Paul E; Elmaadawi, Ahmed Z; Aaronson, Scott T; Schrodt, G Randolph Jr; Holbert, Richard C; Verdoliva, Sarah; Heart, Karen L; Demitrack, Mark A; Strawn, Jeffrey R

Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk

细胞内摄取阻断hERG通道的药物可能会干扰QT间期延长和心律失常风险的评估。

Burashnikov, Alexander; Barajas-Martinez, Hector; Cox, Robert; Demitrack, Mark A; Fossler, Michael J; Kramer, Michael; Kleiman, Robert B; Kowey, Peter; Antzelevitch, Charles

Oliceridine is Associated with Reduced Risk of Vomiting and Need for Rescue Antiemetics Compared to Morphine: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials

与吗啡相比,奥利西啶可降低呕吐风险和使用补救性止吐药的需求:两项3期随机安慰剂和活性对照试验的探索性分析

Beard, Timothy L; Michalsky, Cathy; Candiotti, Keith A; Rider, Paul; Wase, Linda; Habib, Ashraf S; Demitrack, Mark A; Fossler, Michael J; Viscusi, Eugene R

Low Incidence of Opioid-Induced Respiratory Depression Observed with Oliceridine Regardless of Age or Body Mass Index: Exploratory Analysis from a Phase 3 Open-Label Trial in Postsurgical Pain

无论年龄或体重指数如何,使用奥利西啶治疗后观察到的阿片类药物引起的呼吸抑制发生率均较低:一项针对术后疼痛的3期开放标签试验的探索性分析

Brzezinski, Marek; Hammer, Gregory B; Candiotti, Keith A; Bergese, Sergio D; Pan, Peter H; Bourne, Michael H; Michalsky, Cathy; Wase, Linda; Demitrack, Mark A; Habib, Ashraf S

Oliceridine Exhibits Improved Tolerability Compared to Morphine at Equianalgesic Conditions: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials

在等效镇痛条件下,奥利西啶与吗啡相比表现出更好的耐受性:来自两项3期随机安慰剂和活性对照试验的探索性分析

Hammer, Gregory B; Khanna, Ashish K; Michalsky, Cathy; Wase, Linda; Demitrack, Mark A; Little, Roderick; Fossler, Michael J; Ayad, Sabry

A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneous and Oral TRV250, a G Protein-Selective Delta Receptor Agonist, in Healthy Subjects

一项 I 期随机、单盲、安慰剂对照、单次递增剂量研究,旨在评估皮下和口服 TRV250(一种 G 蛋白选择性 Delta 受体激动剂)在健康受试者中的安全性、耐受性和药代动力学。

Fossler, Michael J; Schmith, Virginia; Greene, Stephen A; Lohmer, Lauren; Kramer, Michael S; Arscott, Kelly; James, Ian E; Demitrack, Mark A

Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis

与吗啡相比,奥利西啶术后呼吸抑制发生率较低:一项回顾性病例分析

Bergese, Sergio; Berkowitz, Richard; Rider, Paul; Ladouceur, Martin; Griffith, Suzanne; Segura Vasi, Alvaro; Cochrane, Kristina; Wase, Linda; Demitrack, Mark A; Habib, Ashraf S